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绝经后女性的骨骼质量

Skeletal mass in postmenopausal women.

作者信息

Aloia J F, Cohn S H, Ross P, Vaswani A, Abesamis C, Ellis K, Zanzi I

出版信息

Am J Physiol. 1978 Jul;235(1):E82-7. doi: 10.1152/ajpendo.1978.235.1.E82.

Abstract

The techniques of photon absorptiometry of the radius and total body neutron activation analysis were used for the determination of bone mineral content and total body calcium, respectively. The subjects consisted of 71 normal women who were 1-5 yr postmenopausal and 44 osteoporotic women who had crush fractures of the dorsal spine. Both bone mineral content and total body calcium were corrected for age and body size by using the ratio of observed values to those predicted from previously derived equations. Discrimant analysis involving both osteoporotic and normal postmenopausal women resulted in the successful assignment of 81% of the 115 subjects to their correct group. Statistical analyses of the distribution of the bone mass of the postmenopausal women yielded no evidence to support the hypothesis that a subgroup exists with bone mass levels markedly different from the remainder of the women.

摘要

分别采用桡骨光子吸收测定技术和全身中子活化分析技术来测定骨矿物质含量和全身钙含量。研究对象包括71名绝经后1至5年的正常女性以及44名患有胸椎压缩性骨折的骨质疏松女性。通过将观察值与根据先前推导公式预测的值的比值,对骨矿物质含量和全身钙含量进行年龄和体型校正。对骨质疏松和绝经后正常女性进行判别分析,结果成功地将115名受试者中的81%正确分类到相应组中。对绝经后女性骨量分布的统计分析没有证据支持存在一个骨量水平与其他女性明显不同的亚组这一假设。

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