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人类下丘脑的视交叉上区:与灵长类昼夜节律起搏器同源?

Suprachiasmatic region of the human hypothalamus: homolog to the primate circadian pacemaker?

作者信息

Lydic R, Schoene W C, Czeisler C A, Moore-Ede M C

出版信息

Sleep. 1980;2(3):355-61. doi: 10.1093/sleep/2.3.355.

DOI:10.1093/sleep/2.3.355
PMID:6773133
Abstract

The suprachiasmatic nuclei (SCN) of the hypothalamus in mammals, including nonhuman primates, contain a key pacemaker of the circadian timing system. Examination of the histology of the anterior hypothalamus in human fetal, child, and adult brains indicates that there is a cluster of neurons which may be homologous to SCN. These neurons are more diffusely organized and laterally placed in human brains than is the SCN of nonhuman primates.

摘要

包括非人类灵长类动物在内的哺乳动物下丘脑中的视交叉上核(SCN)包含昼夜节律计时系统的关键起搏器。对人类胎儿、儿童和成人大脑下丘脑前部组织学的检查表明,存在一组可能与SCN同源的神经元。与非人类灵长类动物的SCN相比,这些神经元在人类大脑中的组织更为分散且位于更外侧。

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