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用氢电极技术测量动物局部骨骼肌血流量。

Measurement of local skeletal muscle blood flow in animals by the hydrogen electrode technique.

作者信息

Mishra S K, Haining J L

出版信息

Muscle Nerve. 1980 Jul-Aug;3(4):285-8. doi: 10.1002/mus.880030402.

DOI:10.1002/mus.880030402
PMID:6774245
Abstract

The hydrogen (H2) electrode technique has been applied to the measurement of local skeletal muscle blood flow (LSMBF) in experimental animals (rats, rabbits, and monkeys). LSMBF was measured during resting and postexercise states, following epinephrine injections and during CO2 inhalation. Among the limited sites studied and/or measurements obtained, significant differences in LSMBF were found in only a few instances. During hypercapnia, LSMBF was found to be increased in some muscles in rats and monkeys. The present study demonstrates that the H2 electrode technique is a simple and reliable method for measuring resting and postexercise LSMBF in anesthetized animals. This method provides measurements at discrete loci, is easily reproducible, and causes little trauma.

摘要

氢(H2)电极技术已被应用于测量实验动物(大鼠、兔子和猴子)的局部骨骼肌血流量(LSMBF)。在静息和运动后状态、注射肾上腺素后以及吸入二氧化碳期间测量LSMBF。在所研究的有限部位和/或获得的测量值中,仅在少数情况下发现LSMBF有显著差异。在高碳酸血症期间,发现大鼠和猴子的某些肌肉中的LSMBF增加。本研究表明,H2电极技术是一种测量麻醉动物静息和运动后LSMBF的简单可靠方法。该方法可在离散部位进行测量,易于重复,且造成的创伤很小。

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