MMWR Morb Mortal Wkly Rep. 1996 Nov 22;45(46):1010-3.
Neisseria meningitidis is a leading cause of bacterial meningitis and sepsis in the United States. N. meningitidis is classified into serogroups based on the antigenic characteristics of its capsular polysaccharide. During 1989-1991 in the United States, serogroups B and C accounted for most (91%) of invasive meningococcal disease while serogroup Y caused < 5%; however, during 1992-1995, serogroup Y accounted for an increasing proportion of meningococcal disease. This report describes the epidemiology of serogroup Y meningococcal disease (SYMD) during 1991-1996 in Illinois and Connecticut, which conducted enhanced surveillance through active reviews of clinical records and in areas participating in active laboratory-based surveillance during 1989-1995. The findings indicate a substantial increase in the proportion of meningococcal disease caused by N. meningitidis serogroup Y since 1989.
脑膜炎奈瑟菌是美国细菌性脑膜炎和败血症的主要病因。脑膜炎奈瑟菌根据其荚膜多糖的抗原特性分为不同血清群。1989 - 1991年期间在美国,B群和C群占侵袭性脑膜炎球菌病的大部分(91%),而Y群引起的病例不到5%;然而,在1992 - 1995年期间,Y群在脑膜炎球菌病中所占比例不断增加。本报告描述了1991 - 1996年期间伊利诺伊州和康涅狄格州Y群脑膜炎球菌病(SYMD)的流行病学情况,这两个州通过对临床记录的主动审查以及在1989 - 1995年期间参与基于实验室主动监测的地区进行了强化监测。研究结果表明,自1989年以来,由脑膜炎奈瑟菌Y群引起的脑膜炎球菌病比例大幅增加。