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脑膜炎奈瑟菌生殖道和肛门直肠分离株对青霉素G和四环素M质粒的敏感性降低。

Decreased susceptibility to penicillin G and Tet M plasmids in genital and anorectal isolates of Neisseria meningitidis.

作者信息

Winterscheid K K, Whittington W L, Roberts M C, Schwebke J R, Holmes K K

机构信息

Department of Medicine, University of Washington, Seattle 98195.

出版信息

Antimicrob Agents Chemother. 1994 Jul;38(7):1661-3. doi: 10.1128/AAC.38.7.1661.

Abstract

Genital and anorectal isolates of Neisseria meningitidis were characterized, and their antimicrobial susceptibilities were determined. Twelve of 43 isolates demonstrated moderate susceptibility to penicillin G (MIC range, 0.125 to 0.5 microgram/ml). Two isolates were resistant to tetracycline (MIC, > or = 8 micrograms/ml) and contained plasmids of 25.2 MDa.

摘要

对脑膜炎奈瑟菌的生殖器和肛门直肠分离株进行了特征分析,并测定了它们的抗菌药敏性。43株分离株中有12株对青霉素G表现出中度敏感性(MIC范围为0.125至0.5微克/毫升)。两株分离株对四环素耐药(MIC,≥8微克/毫升),并含有25.2兆道尔顿的质粒。

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