丙戊酸钠与骨髓抑制

Ann Neurol. 1980 Aug;8(2):197-9. doi: 10.1002/ana.410080213.

Bone marrow suppression developed in a patient while she was on a regimen of sodium valproate. In addition, she had high titers of platelet autoantibodies and a coagulopathy, both recognized complications of valproate therapy. It is postulated that this drug was also responsible for the marrow suppression.

一名患者在服用丙戊酸钠期间出现了骨髓抑制。此外，她有高滴度的血小板自身抗体和凝血障碍，这两者都是丙戊酸治疗公认的并发症。据推测，这种药物也是导致骨髓抑制的原因。