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色甘酸钠对犬肺中“C”纤维末梢的作用。

The action of sodium cromoglycate on 'C' fibre endings in the dog lung.

作者信息

Dixon M, Jackson D M, Richards I M

出版信息

Br J Pharmacol. 1980 Sep;70(1):11-3. doi: 10.1111/j.1476-5381.1980.tb10898.x.

DOI:10.1111/j.1476-5381.1980.tb10898.x
PMID:6775722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2044365/
Abstract

The effect has been studied of sodium cromoglycate (SCG) on the activity of 'C' fibre sensory nerve endings in the canine lung. Pretreatment with SCG (100 microgram/kg i.v.) reduced the excitation of these endings by capsaicin (10 microgram/kg i.v.) for approximately 45 min. This property of SCG may explain its ability to suppress certain types of bronchoconstrictor responses in man.

摘要

已对色甘酸钠（SCG）对犬肺中“C”纤维感觉神经末梢活性的影响进行了研究。用SCG（100微克/千克静脉注射）预处理可使辣椒素（10微克/千克静脉注射）对这些末梢的兴奋作用降低约45分钟。SCG的这一特性可能解释了其抑制人类某些类型支气管收缩反应的能力。

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The action of sodium cromoglycate on 'C' fibre endings in the dog lung.色甘酸钠对犬肺中“C”纤维末梢的作用。
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本文引用的文献

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ROLE OF THE PULMONARY ARTERIAL BARORECEPTORS IN THE EFFECTS PRODUCED BY CAPSAICIN IN THE DOG.肺动脉压力感受器在辣椒素对犬产生的效应中的作用
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Mechanics of respiration in unanesthetized guinea pigs.未麻醉豚鼠的呼吸力学
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Receptors in the trachea and bronchi of the cat.猫气管和支气管中的受体。
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Search for evidence of lung chemoreflexes in man: study of respiratory and circulatory effects of phenyldiguanide and lobeline.探寻人类肺化学反射的证据：苯双胍和洛贝林对呼吸及循环系统影响的研究。
Clin Sci. 1972 Feb;42(2):163-77. doi: 10.1042/cs0420163.
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The release of prostaglandins from lung and other tissues.前列腺素从肺和其他组织中的释放。
Ann N Y Acad Sci. 1971 Apr 30;180:363-85. doi: 10.1111/j.1749-6632.1971.tb53205.x.
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Stimulation of 'irritant' receptors and afferent C-fibres in the lungs by prostaglandins.前列腺素对肺部“刺激性”受体和传入C纤维的刺激作用。
Nature. 1976 Dec 2;264(5585):451-3. doi: 10.1038/264451a0.
7
Impulse activity in afferent vagal C-fibres with endings in the intrapulmonary airways of dogs.在犬肺内气道有终末的传入迷走神经C纤维中的冲动活动。
Respir Physiol. 1977 Apr;29(2):125-42. doi: 10.1016/0034-5687(77)90086-x.
8
Stimulation of afferent vagal endings in the intrapulmonary airways by prostaglandin endoperoxide analogues.前列腺素内过氧化物类似物对肺内气道传入迷走神经末梢的刺激作用。
Prostaglandins. 1978 Jan;15(1):131-8. doi: 10.1016/s0090-6980(78)80011-2.
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Reflex bronchoconstriction induced by capsaicin in the dog.辣椒素在犬体内诱发的反射性支气管收缩
J Appl Physiol Respir Environ Exerc Physiol. 1979 Nov;47(5):961-7. doi: 10.1152/jappl.1979.47.5.961.
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The effects of histamine, acetylcholine and 5-hydroxytryptamine on lung mechanics and irritant receptors in the dog.组胺、乙酰胆碱和5-羟色胺对犬肺力学和刺激感受器的影响。
J Physiol. 1979 Feb;287:393-403. doi: 10.1113/jphysiol.1979.sp012666.