色甘酸钠对犬肺中“C”纤维末梢的作用。
The action of sodium cromoglycate on 'C' fibre endings in the dog lung.
作者信息
Dixon M, Jackson D M, Richards I M
出版信息
Br J Pharmacol. 1980 Sep;70(1):11-3. doi: 10.1111/j.1476-5381.1980.tb10898.x.
Abstract
The effect has been studied of sodium cromoglycate (SCG) on the activity of 'C' fibre sensory nerve endings in the canine lung. Pretreatment with SCG (100 microgram/kg i.v.) reduced the excitation of these endings by capsaicin (10 microgram/kg i.v.) for approximately 45 min. This property of SCG may explain its ability to suppress certain types of bronchoconstrictor responses in man.
摘要
已对色甘酸钠（SCG）对犬肺中“C”纤维感觉神经末梢活性的影响进行了研究。用SCG（100微克/千克静脉注射）预处理可使辣椒素（10微克/千克静脉注射）对这些末梢的兴奋作用降低约45分钟。SCG的这一特性可能解释了其抑制人类某些类型支气管收缩反应的能力。
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