Preud'homme J L, Galian A, Danon F, Marti R, Rambaud J C
Cancer. 1980 Oct 15;46(8):1753-8. doi: 10.1002/1097-0142(19801015)46:8<1753::aid-cncr2820460809>3.0.co;2-z.
A case of gastric and lymph node extramedullary plasmacytoma is reported in a young Algerian female. Treatment with cyclophosphamide was ineffective, but rubidazone, followed by a maintenance therapy with prednisone, procarbazine, and vinblastine induced a complete remission. Immunofluorescence studies and biosynthesis experiments in vitro showed that the tumor cells produced and secreted IgA-kappa molecules, whereas no monoclonal immunoglobulin could be found in the serum and gastric juice.
报告了一例年轻阿尔及利亚女性的胃及淋巴结髓外浆细胞瘤病例。环磷酰胺治疗无效，但柔红霉素，随后用泼尼松、丙卡巴肼和长春碱进行维持治疗诱导了完全缓解。免疫荧光研究和体外生物合成实验表明，肿瘤细胞产生并分泌IgA-κ分子，而血清和胃液中未发现单克隆免疫球蛋白。
