Funakoshi N, Kanoh T, Kobayashi Y, Miyake T, Uchino H, Ochi K
Cancer. 1984 Aug 15;54(4):638-43. doi: 10.1002/1097-0142(1984)54:4<638::aid-cncr2820540409>3.0.co;2-a.
A case of gastric plasmacytoma is reported in an 81-year-old woman. Immunofluorescent and immunoelectrophoretic studies showed that the tumor cells produced IgM-lambda molecules, whereas no monoclonal immunoglobulin could be detected both in the serum and in the urine. Of more than 60 reported cases of gastric plasmacytoma, only a few reports referred to the production of monoclonal immunoglobulin by the tumor cells. This case is the first one of IgM-producing gastric plasmacytoma. Moreover, the produced IgM was found to be 7S-IgM. It is extremely rare that 7S-IgM alone is detected in the absence of 19S-IgM.
本文报道了一例81岁女性的胃浆细胞瘤。免疫荧光和免疫电泳研究表明，肿瘤细胞产生IgM-λ分子，而血清和尿液中均未检测到单克隆免疫球蛋白。在已报道的60多例胃浆细胞瘤病例中，仅有少数报道提及肿瘤细胞产生单克隆免疫球蛋白。该病例是首例产生IgM的胃浆细胞瘤。此外，所产生的IgM被发现为7S-IgM。在没有19S-IgM的情况下单独检测到7S-IgM极为罕见。
