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1
Regulation of murine B cells through surface immunoglobulin. I. Monoclonal anti-delta antibody that induces allotype-specific proliferation.通过表面免疫球蛋白对小鼠B细胞的调节。I. 诱导同种异型特异性增殖的单克隆抗δ抗体。
J Exp Med. 1980 Nov 1;152(5):1135-46. doi: 10.1084/jem.152.5.1135.
2
In vivo activation of quiescent B cells by anti-immunoglobulin. I. Induction of latent VH allotype production in adult rabbits by treatment with heterologous antibodies or antibody fragments.抗免疫球蛋白对静止B细胞的体内激活。I. 用异源抗体或抗体片段处理成年兔诱导潜在VH同种异型的产生。
J Immunol. 1987 May 1;138(9):2982-7.
3
Effects of allotype specific anti-IgD on the immune responses of homozygous mice.同种异型特异性抗IgD对纯合小鼠免疫反应的影响。
Ann N Y Acad Sci. 1982;399:304-9. doi: 10.1111/j.1749-6632.1982.tb25683.x.
4
Murine cell surface immunoglobulin: two forms of delta-heavy chain.小鼠细胞表面免疫球蛋白：δ重链的两种形式。
J Immunol. 1979 Sep;123(3):1155-61.
5
A mouse monoclonal antibody specific for an allotypic determinant of the Igha allele of murine IgM: genetic and functional analysis of Igh-6a epitopes using anti-IgM monoclonal antibodies.一种针对小鼠IgM的Igha等位基因同种异型决定簇的小鼠单克隆抗体：使用抗IgM单克隆抗体对Igh-6a表位进行遗传和功能分析。
Hybridoma. 1991 Feb;10(1):121-35. doi: 10.1089/hyb.1991.10.121.
6
Effect of allotype specific anti-IgD on the immune responses of heterozygous mice.同种异型特异性抗IgD对杂合子小鼠免疫反应的影响。
Ann N Y Acad Sci. 1982;399:310-5. doi: 10.1111/j.1749-6632.1982.tb25684.x.
7
The relationship between surface immunoglobulin isotype and immune function of murine B lymphocytes. V. IgD-bearing cells in immunological tolerance.小鼠B淋巴细胞表面免疫球蛋白同种型与免疫功能的关系。V. 免疫耐受中的IgD阳性细胞
Eur J Immunol. 1982 Oct;12(10):838-44. doi: 10.1002/eji.1830121008.
8
Igh-1b-specific CD4+CD8- T cell clones of the Th1 subset selectively suppress the Igh-1b allotype in vivo.Th1亚群的Igh-1b特异性CD4+CD8-T细胞克隆在体内选择性抑制Igh-1b同种异型。
Eur J Immunol. 1991 Oct;21(10):2365-71. doi: 10.1002/eji.1830211011.
9
The activation of murine B cells: the role of surface immunoglobulins.小鼠B细胞的激活：表面免疫球蛋白的作用
Immunol Rev. 1980;52:211-31. doi: 10.1111/j.1600-065x.1980.tb00336.x.
10
Role of IgD in the immune response and tolerance. II. Precursor analysis of murine B cells separated on the basis of surface IgD or treated with an anti-delta serum.IgD在免疫应答和免疫耐受中的作用。II. 基于表面IgD分离或用抗δ血清处理的小鼠B细胞的前体分析。
Eur J Immunol. 1978 Jan;8(1):13-6. doi: 10.1002/eji.1830080104.

引用本文的文献

1
Basophils initiate IL-4 production during a memory T-dependent response.嗜碱性粒细胞在记忆性T细胞依赖性反应过程中启动白细胞介素-4的产生。
J Exp Med. 2004 Oct 4;200(7):857-70. doi: 10.1084/jem.20040598.
2
Glycoinositolphospholipids from Trypanosoma cruzi induce B cell hyper-responsiveness in vivo.来自克氏锥虫的糖基肌醇磷脂在体内诱导B细胞超反应性。
Glycoconj J. 2000 Oct;17(10):727-34. doi: 10.1023/a:1011082925179.
3
Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody.抗白细胞介素7单克隆抗体对小鼠体内B淋巴细胞和T淋巴细胞生成的抑制作用。
J Exp Med. 1993 Jul 1;178(1):257-64. doi: 10.1084/jem.178.1.257.
4
Induction of a B-lymphocyte receptor for a T cell-replacing factor by the crosslinking of surface IgD.通过表面IgD交联诱导T细胞替代因子的B淋巴细胞受体。
Proc Natl Acad Sci U S A. 1983 Jan;80(1):293-7. doi: 10.1073/pnas.80.1.293.
5
T cell-derived B cell growth and differentiation factors. Dichotomy between the responsiveness of B cells from adult and neonatal mice.T细胞衍生的B细胞生长和分化因子。成年小鼠和新生小鼠B细胞反应性的差异。
J Exp Med. 1983 Feb 1;157(2):600-12. doi: 10.1084/jem.157.2.600.
6
Biological effects of antibodies to lymphocyte surface receptors.抗淋巴细胞表面受体抗体的生物学效应。
Springer Semin Immunopathol. 1982;5(4):463-75. doi: 10.1007/BF01857431.
7
Studies of surface immunoglobulin-dependent B cell activation.表面免疫球蛋白依赖性B细胞活化的研究。
Immunol Res. 1988;7(2):136-51. doi: 10.1007/BF02918097.
8
Exposure to crosslinked IgD induces receptors for IgD on T cells in vivo and in vitro.暴露于交联的IgD可在体内和体外诱导T细胞上的IgD受体。
Proc Natl Acad Sci U S A. 1988 Jan;85(2):559-63. doi: 10.1073/pnas.85.2.559.
9
Activation and proliferation signals in mouse B cells. V.A. comparison of the effects of intact (IgG) and F (ab')2 anti-mu or anti-delta antibodies.小鼠B细胞中的激活和增殖信号。V.A. 完整（IgG）和F（ab'）2抗μ或抗δ抗体作用效果的比较。
Immunology. 1985 Apr;54(4):677-83.
10
Release of IgD-binding factor by T cells under the influence of interleukin 2, interleukin 4, or cross-linked IgD.在白细胞介素2、白细胞介素4或交联IgD的影响下，T细胞释放IgD结合因子。
Proc Natl Acad Sci U S A. 1988 Dec;85(23):9179-83. doi: 10.1073/pnas.85.23.9179.

本文引用的文献

1
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
Nature. 1970 Aug 15;227(5259):680-5. doi: 10.1038/227680a0.
2
The immunologic response to xenografts. Recognition of mouse H-2 histocompatibility antigens by the rat.对异种移植的免疫反应。大鼠对小鼠H-2组织相容性抗原的识别。
J Immunol. 1971 Aug;107(2):481-92.
3
Cloning of mouse myeloma cells and detection of rare variants.小鼠骨髓瘤细胞的克隆及稀有变体的检测
J Cell Physiol. 1972 Jun;79(3):429-40. doi: 10.1002/jcp.1040790313.
4
Separation of mouse spleen cells by passage through columns of sephadex G-10.通过葡聚糖凝胶G - 10柱对小鼠脾细胞进行分离。
J Immunol Methods. 1974 Aug;5(3):239-47. doi: 10.1016/0022-1759(74)90108-2.
5
Membrane immunoglobulins and antigen receptors on B and T lymphocytes.B淋巴细胞和T淋巴细胞上的膜免疫球蛋白及抗原受体。
Adv Immunol. 1974;19(0):67-216. doi: 10.1016/s0065-2776(08)60252-7.
6
The distribution of alloantigenic specificities of native H-2 products.天然H-2产物的同种抗原特异性分布。
J Immunol. 1972 Mar;108(3):596-600.
7
Continuous cultures of fused cells secreting antibody of predefined specificity.分泌预定义特异性抗体的融合细胞的连续培养物。
Nature. 1975 Aug 7;256(5517):495-7. doi: 10.1038/256495a0.
8
Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A.用葡萄球菌蛋白A-抗体吸附剂从细胞中快速分离抗原：抗体-抗原复合物与蛋白A相互作用的参数
J Immunol. 1975 Dec;115(6):1617-24.
9
One non-specific signal triggers b lymphocytes.一种非特异性信号触发B淋巴细胞。
Transplant Rev. 1975;23:126-37.
10
Immunoglobulin-receptors revisited.免疫球蛋白受体再探讨。
Science. 1975 Sep 19;189(4207):964-9. doi: 10.1126/science.1083069.

通过表面免疫球蛋白对小鼠B细胞的调节。I. 诱导同种异型特异性增殖的单克隆抗δ抗体。

Regulation of murine B cells through surface immunoglobulin. I. Monoclonal anti-delta antibody that induces allotype-specific proliferation.

作者信息

Zitron I M, Clevinger B L

出版信息

J Exp Med. 1980 Nov 1;152(5):1135-46. doi: 10.1084/jem.152.5.1135.

DOI:10.1084/jem.152.5.1135
PMID:6776225
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2185997/
Abstract

We describe the identification of a monoclonal antibody that recognizes a determinant on the delta chain of mice of the Iga, allotype groups. The monoclonal Ig in soluble form induces allotype-specific proliferation by splenic B lymphocytes from normal animals of these haplotypes. Spleen cells from mice bearing the X-linked defect of CBA/N mice fail to respond, although they bear the determinant. Proliferation is independent of T lymphocytes. The data indicate a direct triggering function for sIgD.

摘要

我们描述了一种单克隆抗体的鉴定，该抗体识别Iga同种异型组小鼠δ链上的一个决定簇。可溶性形式的单克隆Ig可诱导这些单倍型正常动物脾脏B淋巴细胞发生同种异型特异性增殖。携带CBA/N小鼠X连锁缺陷的小鼠脾脏细胞虽然带有该决定簇，但无反应。增殖不依赖于T淋巴细胞。这些数据表明sIgD具有直接触发功能。