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颈段食管吞咽困难:环咽肌切开术的适应证及结果

Cervical esophageal dysphagia: indications for and results of cricopharyngeal myotomy.

作者信息

Ellis F H, Crozier R E

出版信息

Ann Surg. 1981 Sep;194(3):279-89. doi: 10.1097/00000658-198109000-00005.

Abstract

Twenty patients with cervical esophageal dysphagia were treated by cricopharyngeal myotomy. Of these 20 patients, ten had pharyngoesophageal diverticula, four had a hypertensive upper esophageal sphincter (UES), four had bulbar palsy, and two has miscellaneous forms of cricopharyngeal dysfunction. Preoperative esophageal manometric examination revealed mean UES pressures of 37.2 mmHg +/- 4.8 SEM in patients with diverticula-markedly lower (p = 0.01) than in normal patients (55.9 mmHg +/- 5.0 SEM). In patients with hypertensive UES the mean pressure was 166.2 mmHg +/- 13.4, significantly higher (p less than 0.001) than normal. Incoordination of the deglutitive response of the UES characterised by premature relaxation and contraction was present in all patients with diverticula and in one other patient. Another patient exhibited incomplete sphincteric relaxation (achalasia). A 4-5 cm myotomy of the cricopharyngeus muscle and adjacent esophageal muscle was performed in all patients. On the patients with diverticula two also had diverticulectomy. No patient with bulbar palsy was benefited. All other patients were relieved of dysphagia by the operation, with the exception of one patient with a diverticulum. A subsequent diverticulectomy was required in this patient. Postoperative manometric examination revealed an average decrease in UES pressure of 63% and an average decreased in length of the high pressure zone of 1.4 cm.

摘要

20例颈段食管吞咽困难患者接受了环咽肌切开术治疗。在这20例患者中,10例有咽食管憩室,4例有高压性上食管括约肌(UES),4例有延髓麻痹,2例有其他形式的环咽肌功能障碍。术前食管测压检查显示,憩室患者的UES平均压力为37.2 mmHg±4.8 SEM,明显低于正常患者(55.9 mmHg±5.0 SEM,p = 0.01)。高压性UES患者的平均压力为166.2 mmHg±13.4,明显高于正常水平(p<0.001)。所有憩室患者及另外1例患者存在UES吞咽反应不协调,表现为过早松弛和收缩。另1例患者表现为括约肌不完全松弛(贲门失弛缓症)。所有患者均进行了4 - 5 cm的环咽肌及相邻食管肌切开术。有憩室的患者中,2例还进行了憩室切除术。延髓麻痹患者均未从手术中获益。除1例有憩室的患者外,所有其他患者术后吞咽困难均得到缓解。该患者随后需要进行憩室切除术。术后测压检查显示,UES压力平均下降63%,高压区长度平均缩短1.4 cm。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/045b/1345350/00dad08148ae/annsurg00211-0040-a.jpg

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