Cinefro R J, Frenkel M
Ann Ophthalmol. 1978 Apr;10(5):559-63.
A 57-year-old white man presented with unilateral optic neuritis. General physical examination and neurologic consultation revealed no further findings. Laboratory investigation, however, yielded an elevated sedimentation rate, positive LE preparation, elevated ANA titer, false-positive VDRL, and red blood cell casts in the urine. A diagnosis of systemic lupus erythematosus (SLE) was made. The patient was treated with sub-Tenon and systemic corticosteroids. There was a moderate improvement in central visual acuity. The suspected pathophysiology of SLE is reviewed. The papillitis presumably reflects the generalized vasculitis of SLE and may be responsive to corticosteroids as are other signs and symptoms of this disease.
一名57岁白人男性因单侧视神经炎就诊。全身体格检查和神经科会诊未发现其他异常。然而，实验室检查显示血沉升高、狼疮细胞检查阳性、抗核抗体滴度升高、性病研究实验室玻片试验假阳性以及尿中出现红细胞管型。诊断为系统性红斑狼疮（SLE）。该患者接受了球后和全身皮质类固醇治疗。中心视力有中度改善。本文回顾了SLE可能的病理生理学机制。视乳头炎大概反映了SLE的全身性血管炎，并且可能与该疾病的其他体征和症状一样对皮质类固醇有反应。
