Künstler K
Arzneimittelforschung. 1980;30(10):1717-8.
Male and female NMRI mice received a daily dose of 100 mg/kg thioctic acid i.v., s.c., or i.p. for five days after transplantation with Ehrlich ascites carcinoma. Median survival time, increase in body weight, and volume and cellular content of the ascitic fluid were determined. Except a decrease in survival time which was due to the high dose of the thiotic acid but not to an increased growth of tumor cells, there was no significant difference between treated animals and control groups.
在接种艾氏腹水癌后，雄性和雌性NMRI小鼠每天通过静脉注射、皮下注射或腹腔注射给予100毫克/千克硫辛酸，持续五天。测定了中位生存时间、体重增加以及腹水的体积和细胞含量。除了由于高剂量硫辛酸导致生存时间缩短而非肿瘤细胞生长增加外，治疗组动物与对照组之间没有显著差异。
