Malcolm R E, Sillett R W, Turner J A, Ball K P
Psychopharmacology (Berl). 1980;70(3):295-6. doi: 10.1007/BF00427889.
Two hundred and ten subjects entered a trial to test the use of a chewing gum containing nicotine as an aid to stopping smoking. They were divided into three groups: nicotine chewing gum, placebo chewing gum, and control. The trial was double blind between the two chewing gum groups. After 1 month the percentage of confirmed non-smokers in the nicotine gum group was 34%, in placebo chewing gum group 37% and the control group 24%. By 6 months most of the non-smokers had relapsed, but the nicotine gum group (23%) was more successful than the placebo (5% or the control group (14%).
210名受试者参与了一项试验,以测试含有尼古丁的口香糖作为戒烟辅助手段的效果。他们被分为三组:尼古丁口香糖组、安慰剂口香糖组和对照组。两个口香糖组的试验是双盲的。1个月后,尼古丁口香糖组中确认戒烟的比例为34%,安慰剂口香糖组为37%,对照组为24%。到6个月时,大多数戒烟者都复吸了,但尼古丁口香糖组(23%)比安慰剂组(5%)和对照组(14%)更成功。