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戊巴比妥与遗忘

Amylobarbitone and forgetting.

作者信息

Sahgal A, Hulme M, Iversen S D

出版信息

Psychopharmacology (Berl). 1980;71(2):189-93. doi: 10.1007/BF00434410.

Abstract

In an earlier report (Hulme et al. 1979), we argued that sodium amylobarbitone (SAB) affects the acquisition of information. That conclusion was based on the finding that SAB produces rates of forgetting that are similar to control, thereby ruling out storage (and possibly retrieval) deficiencies which would predict dissimilar rates. However, it is possible that the rate of forgetting is itself influenced by the amount of information that actually entered store in the first place, and SAB reduces this by affecting acquisition. The possibility that both acquisition and storage could therefore have been affected was explored by equating control and drug zero delay performance, which was achieved by lowering the performance of control subjects. Nonetheless, subsequent rates of forgetting remained similar, thereby strengthening the acquistion hypothesis.

摘要

在一份较早的报告中(休姆等人,1979年),我们认为戊巴比妥钠(SAB)会影响信息的获取。这一结论是基于以下发现:SAB产生的遗忘率与对照组相似,从而排除了预测不同遗忘率的存储(以及可能的检索)缺陷。然而,遗忘率本身有可能受到最初实际进入存储的信息量的影响,而SAB通过影响获取来减少这一信息量。因此,通过使对照组和药物零延迟表现相等来探究获取和存储都可能受到影响的可能性,这是通过降低对照组受试者的表现来实现的。尽管如此,随后的遗忘率仍然相似,从而强化了获取假说。

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