[抗血清及免疫球蛋白对铜绿假单胞菌黏液抗原的保护特性的影响]
[Effect of the protective properties of antisera and immunoglobulin to antigens of Pseudomonas aeruginosa slime].
作者信息
Zaĭdner I G, Stanislavskiĭ E S, Gladus M A
出版信息
Zh Mikrobiol Epidemiol Immunobiol. 1980 Oct(10):52-7.
The protective activity of antiserum and immunoglobulin to the toxic components of P. aeruginosa slime was studied in experiments on passive mouse protection. Sheep antiserum, or immunoglobulin obtained from this antiserum, was found to have a pronounced protective effect (antimicrobial action) in the infection of mice with a homologous or heterologous P. aeruginosa strain. Normal sheep serum and its globulin fraction also had a definite unspecific antimicrobial and antitoxic activity as revealed in experiments on the passive protection of mice infected with P. aeruginosa.
在小鼠被动保护实验中，研究了抗血清和免疫球蛋白对铜绿假单胞菌黏液毒性成分的保护活性。发现绵羊抗血清或从该抗血清中获得的免疫球蛋白在同源或异源铜绿假单胞菌菌株感染小鼠时具有显著的保护作用（抗菌作用）。正常绵羊血清及其球蛋白组分在铜绿假单胞菌感染小鼠的被动保护实验中也显示出一定的非特异性抗菌和抗毒活性。
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