Zaĭdner I G, Palkina N A, Stanislavskiĭ E S, Landsman N M
Zh Mikrobiol Epidemiol Immunobiol. 1981 Apr(4):92-7.
P. aeruginosa slime has been separated into fractions XM-300 (3 X 10(5) daltons and more), XM-100 (1 X 10(5) = 3 X 10(5) daltons), PM-30 (3 X 10(4) = 1 X 10(5) daltons) and PM-10, (1 X 10(4) = 3 X 10(4) daltons) by ultrafiltration. The high-molecular slime components (3 X 10(4) daltons and more) have been found to be serologically more active than the low-molecular components (1 X 10(4) = 3 X 10(4) daltons). As shown in experiments on mice, both high-molecular toxic and low-molecular nontoxic slime components have protective activity, but the high-molecular components are more active than the low-molecular ones. The slime components stimulate the formation of immunity to homologous and partially heterologous P. aeruginosa strains in mice. Antigenic relationship between the slime components (especially the high-molecular ones) and the corresponding lipopolysaccharides has been noted.
通过超滤，铜绿假单胞菌黏液已被分离成XM - 300（3×10⁵道尔顿及以上）、XM - 100（1×10⁵ = 3×10⁵道尔顿）、PM - 30（3×10⁴ = 1×10⁵道尔顿）和PM - 10（1×10⁴ = 3×10⁴道尔顿）几个组分。已发现高分子量黏液成分（3×10⁴道尔顿及以上）在血清学上比低分子量成分（1×10⁴ = 3×10⁴道尔顿）更具活性。如在小鼠实验中所示，高分子量有毒和低分子量无毒黏液成分均具有保护活性，但高分子量成分比低分子量成分活性更强。黏液成分能刺激小鼠对同源和部分异源铜绿假单胞菌菌株产生免疫。已注意到黏液成分（尤其是高分子量成分）与相应脂多糖之间的抗原关系。
