Gill B S, Bansal G C, Bhattacharyulu Y, Kaur D, Singh A
Res Vet Sci. 1980 Jul;29(1):93-7.
The immunological relationship between the Ludhiana and Hissar strains, and between the Uruli-Kanchan, Bangalore and Jaipur strains of Theileria annulata was studied. Calves were immunised against the Ludhiana strain by the infection-treatment method, against the Uruli-Kanchan strain by the infection-treatment method or by untreated low-grade infection and against the Jaipur strain by untreated low-grade infection. After 45 days, groups of immune calves and susceptible controls were challenged with 10-tick equivalent stabilates. The ensuing host responses, body temperature, swelling of the regional lymph node, appearance of schizonts in the regional lymph node and piroplasms in blood and mortality, were studied. All five strains proved very virulent and produced severe disease in susceptible calves. Immunisation with the Ludhiana, Uruli-Kanchan and Jaipur strains conferred absolute protection against severe homologous challenges. Immunisation with the Ludhiana and Uruli-Kanchan strains conferred substantial protection against heterologous challenges with the Hissar strain, and the Bangalore and Jaipur strains, respectively. Immunisation with the Uruli-Kanchan strain gave less protection against heterologous challenge with the Jaipur strain and vice versa as some of the challenged calves showed slight swelling of the regional lymph node, two had fever, all exhibited a low-grade parasitaemia and four developed anaemia.
对环形泰勒虫卢迪亚纳株和希萨尔株之间，以及乌鲁利 - 坎钱株、班加罗尔株和斋浦尔株之间的免疫关系进行了研究。通过感染 - 治疗法用卢迪亚纳株对犊牛进行免疫，用感染 - 治疗法或未经处理的轻度感染用乌鲁利 - 坎钱株对犊牛进行免疫，用未经处理的轻度感染用斋浦尔株对犊牛进行免疫。45天后，用相当于10只蜱的稳定株对免疫犊牛组和易感对照组进行攻毒。研究了随后的宿主反应、体温、局部淋巴结肿胀、局部淋巴结中裂殖体的出现、血液中梨形虫以及死亡率。所有五个菌株在易感犊牛中都表现出很强的毒性并引发严重疾病。用卢迪亚纳株、乌鲁利 - 坎钱株和斋浦尔株免疫可对严重的同源攻毒提供绝对保护。用卢迪亚纳株和乌鲁利 - 坎钱株免疫分别对希萨尔株、班加罗尔株和斋浦尔株的异源攻毒提供了实质性保护。用乌鲁利 - 坎钱株免疫对斋浦尔株的异源攻毒提供的保护较少，反之亦然，因为一些攻毒犊牛的局部淋巴结出现轻微肿胀，两只出现发热，所有犊牛都表现出轻度寄生虫血症，四只出现贫血。
