Latchaw R E, L'Heureux P R, Young G, Priest J R
AJNR Am J Neuroradiol. 1982 Nov-Dec;3(6):623-30.
Neuroblastoma may be extremely difficult to recognize, particularly when the tumor presents as a primary central nervous system disease. Central nervous system involvement may be considered as primary intracerebral neuroblastoma, metastases to the cranium from an occult primary, primary intraorbital neuroblastoma originating in the ciliary ganglion, metastatic intraorbital neuroblastoma from an occult primary, primary intraspinal neuroblastoma originating in dorsal root ganglia, intraspinal metastatic disease, and distant effects such as myoclonic encephalopathy. Primary neuroblastoma within the ciliary ganglion and primary intraspinal neuroblastoma are extremely rare entities. Illustrative cases the demonstrate the broad spectrum of neurologic presentations are offered. The second known report of neuroblastoma in association with primary pulmonary hypoventilation (Ondine curse) is included.
神经母细胞瘤可能极难识别，尤其是当肿瘤表现为原发性中枢神经系统疾病时。中枢神经系统受累可被视为原发性脑内神经母细胞瘤、隐匿性原发灶转移至颅骨、起源于睫状神经节的原发性眶内神经母细胞瘤、隐匿性原发灶转移至眶内的转移性眶内神经母细胞瘤、起源于背根神经节的原发性脊髓内神经母细胞瘤、脊髓内转移性疾病以及诸如肌阵挛性脑病等远处效应。睫状神经节内的原发性神经母细胞瘤和原发性脊髓内神经母细胞瘤是极其罕见的实体。文中提供了说明性病例，展示了广泛的神经学表现。其中包括神经母细胞瘤与原发性肺通气不足（翁丁咒诅）相关的第二例已知报告。
