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英国预防亚洲佝偻病政策:对格拉斯哥佝偻病防治运动的初步评估

Policy for prevention of Asian rickets in Britain: a preliminary assessment of the Glasgow rickets campaign.

作者信息

Dunnigan M G, McIntosh W B, Sutherland G R, Gardee R, Glekin B, Ford J A, Robertson I

出版信息

Br Med J (Clin Res Ed). 1981 Jan 31;282(6261):357-60. doi: 10.1136/bmj.282.6261.357.

DOI:10.1136/bmj.282.6261.357
PMID:6780022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1504195/
Abstract

Evidence of continuing hospital admissions of patients with Asian rickets and osteomalacia led to a further attempt to provide more effective preventive measures for the Glasgow Asian community. Dose-response studies showed that the equivalent of 10 microgram of vitamin D daily would provide effective prophylaxis, and a general practice survey showed that self-administered vitamin D supplements would reduce the prevalence and severity of Asian rickets. A multidisciplinary working group devised a preventive campaign based on the free issue of vitamin D supplements on demand to children who required them. Supported by a health education programme for community health personnel and the Asian community, the first 16 months of the campaign produced an eight-fold rise in the issue of supplements to older Asian children and a 33% increase in their issue to infants of all ethnic groups. Because more children are receiving vitamin D supplementation the campaign seems likely to reduce the prevalence of Asian rickets in Glasgow.

摘要

持续有亚洲儿童患佝偻病和骨软化症而住院的情况,这促使人们进一步努力为格拉斯哥的亚洲社区提供更有效的预防措施。剂量反应研究表明,每日补充相当于10微克的维生素D可提供有效的预防作用,一项全科医疗调查显示,自行服用维生素D补充剂可降低亚洲儿童佝偻病的发病率和严重程度。一个多学科工作小组设计了一项预防活动,根据需要为有需求的儿童免费发放维生素D补充剂。在针对社区卫生人员和亚洲社区的健康教育计划的支持下,该活动开展的头16个月里,向年长亚洲儿童发放的补充剂增加了八倍,向所有种族婴儿发放的补充剂增加了33%。由于有更多儿童正在接受维生素D补充,该活动似乎有可能降低格拉斯哥亚洲儿童佝偻病的发病率。

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本文引用的文献

1
Late rickets and osteomalacia in the Pakistani community in Glasgow.格拉斯哥巴基斯坦社区的晚发性佝偻病和骨软化症
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Rickets and osteomalacia in the Glasgow Pakistani community, 1961-71.1961 - 1971年格拉斯哥巴基斯坦社区的佝偻病和骨软化症
Br Med J. 1972 Jun 17;2(5815):677-80. doi: 10.1136/bmj.2.5815.677.
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Plasma calcium, magnesium, phosphorus, and alkaline phosphatase levels in normal British schoolchildren.英国正常学童的血浆钙、镁、磷及碱性磷酸酶水平
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A competitive protein-binding assay for 25-hydroxycholecalciferol and 25-hydroxyergocalciferol in serum.血清中25-羟基胆钙化醇和25-羟基麦角钙化醇的竞争性蛋白结合测定法。
Clin Chim Acta. 1974 Jul 31;54(2):235-42. doi: 10.1016/0009-8981(74)90241-1.
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A rapid assay for 25-OH-vitamin D3 without preparative chromatography.一种无需制备色谱法的25-羟基维生素D3快速检测方法。
J Clin Endocrinol Metab. 1974 Jun;38(6):1046-51. doi: 10.1210/jcem-38-6-1046.
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Prevention of rickets and osteomalacia in Asians.
Lancet. 1977 Aug 20;2(8034):412-3. doi: 10.1016/s0140-6736(77)90355-5.
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Prevention of vitamin-D deficiency in Asians.预防亚洲人群维生素D缺乏症。
Lancet. 1976 May 29;1(7970):1145-8. doi: 10.1016/s0140-6736(76)91539-7.