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危重症患者的脂质输注。对血流动力学和肺气体交换的急性影响。

Lipid infusion in critically ill patients. Acute effects on hemodynamics and pulmonary gas exchange.

作者信息

Järnberg P O, Lindholm M, Eklund J

出版信息

Crit Care Med. 1981 Jan;9(1):27-31. doi: 10.1097/00003246-198101000-00007.

DOI:10.1097/00003246-198101000-00007
PMID:6780264
Abstract

Hemodynamics, pulmonary diffusing capacity (DLCO) blood gases, oxygen consumption (VO2) and carbon dioxide excretion (VCO2) were studied in healthy volunteers and ventilator-treated, critically ill patients before and during infusion of lipid emulsion for 4 h. Triglyceride levels rose from 1.0 mmole/L to 8.5 mmole/L in the volunteers and from 1.4 mmole/L to 6.3 mmole/L in the patients after h. No adverse effects on cardiovascular performance were observed. Increases in VO2, and VCO2 and cardiac output were found in both groups, while RQ remained constant. No changes in DLCO and blood gases occurred.

摘要

在健康志愿者以及接受机械通气治疗的重症患者中,于输注脂质乳剂前及输注4小时期间,对血流动力学、肺弥散容量(DLCO)、血气、耗氧量(VO2)及二氧化碳排出量(VCO2)进行了研究。输注4小时后,志愿者的甘油三酯水平从1.0毫摩尔/升升至8.5毫摩尔/升,患者的甘油三酯水平从1.4毫摩尔/升升至6.3毫摩尔/升。未观察到对心血管功能有不良影响。两组均发现VO2、VCO2及心输出量增加,而呼吸商(RQ)保持不变。DLCO及血气未发生变化。

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