Rietbrock N, Alken R G
MMW Munch Med Wochenschr. 1980 Nov 14;122(46):1624-6.
31 hospitalized patients treated with beta-methyl digoxin and 34 treated with beta-acetyl digoxin were examined for color vision disturbances and compared with a control group (n = 17). The serum digoxin concentration was determined radioimmunologically. A significant correlation (p less than 0,01) was found between the severeness of the disturbances in color vision and the concentration of digoxin in the serum. The disturbances concerned different wave length regions. The lapse of time for disturbances in the distinguishing colors is being described in a case of suicidal intoxication.
对31例接受β-甲基地高辛治疗和34例接受β-乙酰地高辛治疗的住院患者进行了色觉障碍检查,并与一个对照组(n = 17)进行了比较。采用放射免疫法测定血清地高辛浓度。发现色觉障碍的严重程度与血清地高辛浓度之间存在显著相关性(p < 0.01)。这些障碍涉及不同的波长区域。在一例自杀性中毒病例中描述了辨别颜色障碍出现的时间间隔。