Monn E
Acta Paediatr Scand. 1981 Jan;70(1):39-42. doi: 10.1111/j.1651-2227.1981.tb07170.x.
Two boys with classical NDI have been treated with prostaglandin synthetase inhibitors. A boy, 7 years old, was treated with low solute-load diet and diuretics from his first year of life. His main complaint was nocturnal enuresis. He responded within one day to indomethacin 25 mg twice daily, and the urine volume was reduced from 4 1/2--6 litre/day to 2 1/2--3 litre/day. There is almost no enuresis. A boy, 7 months old, had a basal daily urine volume of 1.6--1.8 litre. A low solute-load diet and diuretics reduced urine volume to 1 litre, but he still needed gastric tube feeding. With the addition of acetylsalicylic acid, 75 mg three times daily, the urine volume was reduced to 600 ml, and he needed no more tube feeding. Both boys are doing well on the above-mentioned regimens, and no side effects have been observed after 1 year of treatment.
两名患有典型肾性尿崩症（NDI）的男孩接受了前列腺素合成酶抑制剂治疗。一名7岁男孩从1岁起就接受低溶质负荷饮食和利尿剂治疗。他的主要症状是夜间遗尿。他在开始每天两次服用25毫克吲哚美辛后的一天内就有了反应，尿量从每天4.5 - 6升减少到2.5 - 3升。几乎没有遗尿现象了。一名7个月大的男孩基础日尿量为1.6 - 1.8升。低溶质负荷饮食和利尿剂使尿量减少到1升，但他仍需要鼻饲。每天三次添加75毫克乙酰水杨酸后，尿量减少到600毫升，并且他不再需要鼻饲。两名男孩在上述治疗方案下情况良好，治疗1年后未观察到副作用。
