琼脂凝胶免疫扩散试验在犬芽生菌病诊断中的评估
Evaluation of the agar-gel immunodiffusion test in the diagnosis of canine blastomycosis.
作者信息
Legendre A M, Becker P U
出版信息
Am J Vet Res. 1980 Dec;41(12):2109-11.
PMID:6782921
Abstract
The agar-gel immunodiffusion test was used to evaluated 35 dogs with histopathologically confirmed blastomycosis and 98 dogs without blastomycosis. The test had a sensitivity of 91% and a specificity of 96%. Thirteen of the dogs treated for blastomycosis were tested at 6 to 33 months after treatment with amphotericin B. Ten of 13 dogs became seronegative and 3, though clinically normal, remained seropositive at 19, 20, and 20 months, respectively, after amphotericin treatment.
摘要
采用琼脂凝胶免疫扩散试验对35只经组织病理学确诊为芽生菌病的犬和98只无芽生菌病的犬进行评估。该试验的敏感性为91%，特异性为96%。对13只接受芽生菌病治疗的犬在使用两性霉素B治疗后6至33个月进行检测。13只犬中有10只血清学转为阴性，3只虽然临床正常，但在两性霉素治疗后分别于19、20和20个月仍保持血清学阳性。
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