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[Mechanism of formation of epileptic activity complexes in the cerebral cortex under the influence of a determinant focus].

作者信息

Kryzhanovskiĭ G N, Makul'kin R F, Shandra A A, Boĭko D V

出版信息

Biull Eksp Biol Med. 1978;86(7):14-9.

PMID:678643
Abstract

It was shown in the experiments on cats anesthetized by nembutal that by forming a hyperactive focus with a high level of excitation in the temporal cortex and a number of foci with a less higher level of the excitation in other parts of neocortex, it is possible to create a functional complex, working in a single routine, determined by the activity of hyperactive focus. The latter plays a role of a determinant structure. The inhibition of the determinant focus results in the disturbance of the epileptic complex. Focus nature has no sufficient importance in the realization of the following interrelations: both the determinant focus and dependent foci may be created by means of strychnin and penicillin, disturbing different forms of the inhibition. The results of our investigations evidence a common conception on the role of determinant structures in the activity of the nervous system.

摘要

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