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[大脑皮质中癫痫活动功能复合体形成过程中过度活跃决定结构的作用]

[Role of hyperactive determinant structures in the creation of functional complexes of seizure activity in the cerebral cortex].

作者信息

Kryzhanovskiĭ G N, Makul'kin R F, Shandra A A

出版信息

Biull Eksp Biol Med. 1977 Jan;83(1):5-10.

PMID:851606
Abstract

Experiments were conducted on cats; foci of increased excitability working in the individual activity regimens were created by the subconvulsive strychminization. A focus of more powerful excitation induced also by means of strychine played the role of a determinant dispatch station (DDS). Its importance consists in determining the character of the other excitation foci activity in enhancing the excitation in them, in uniting them into a functional complex, and in determining the character of the whole complex activity. This complex can be destroyed by nembutal suppression of DDS. Exclusion of any other destination stations included into the complex failed to effect this complex.

摘要

在猫身上进行了实验;通过亚惊厥剂量的士的宁化在个体活动方案中创建了兴奋性增加的病灶。同样通过士的宁诱导产生的更强有力的兴奋灶起到了决定性调度站(DDS)的作用。其重要性在于,在增强其他兴奋灶的兴奋时,确定它们的活动特征,将它们联合成一个功能复合体,并确定整个复合体活动的特征。这种复合体可通过戊巴比妥对DDS的抑制作用而被破坏。排除复合体中包含的任何其他目的地站均未能影响该复合体。

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