Jennett B, Hessett C
Br Med J (Clin Res Ed). 1981 Aug 1;283(6287):359-62. doi: 10.1136/bmj.283.6287.359.
The diagnostic mix of 1228 brain-dead renal donors in Britain was similar to that of 479 cases of brain death recently reported from three neurosurgical units. About half the donors came from non-teaching hospitals without a neurosurgical unit, many of them small and distant from the centre. The different circumstances that preceded brain deaths were examined--namely, diagnosis and whether the fatal ictus of brain damage occurred when the patient was already in hospital--to explain why donors spend varying times on the ventilator. Head injuries accounted for half the donors, and intracranial haemorrhage for almost a third. While many potential donors are not made available, the size of the pool has been overestimated, particularly in regard to head injury. Reduction in organ donation since "Panorama" has been very uneven, with some places increasing their yield; this suggests reluctance of doctors to initiate donation rather than relatives withholding permission.
英国1228例脑死亡肾供者的诊断构成与最近三家神经外科单位报告的479例脑死亡病例相似。约一半的供者来自没有神经外科单位的非教学医院,其中许多医院规模小且距离中心较远。研究了脑死亡之前的不同情况,即诊断以及脑损伤的致命发作是否发生在患者已住院时,以解释供者使用呼吸机时间不同的原因。头部损伤占供者的一半,颅内出血占近三分之一。虽然许多潜在供者未被利用,但供者库的规模被高估了,尤其是在头部损伤方面。自《全景》节目播出以来,器官捐献的减少情况非常不均衡,有些地方的捐献量有所增加;这表明医生不愿启动捐献,而非亲属拒绝同意。