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淋病奈瑟菌血清抗性的遗传学:sac-1基因座

Genetics of serum resistance in Neisseria gonorrhoeae: the sac-1 genetic locus.

作者信息

Cannon J G, Lee T J, Guymon L F, Sparling P F

出版信息

Infect Immun. 1981 May;32(2):547-52. doi: 10.1128/iai.32.2.547-552.1981.

Abstract

A genetic locus affecting susceptibility to the bactericidal activity of normal human serum has been designated sac-1. This locus was shown to be closely linked to, but not identical with, a second locus (designated nmp-2) that affects protein 1 of the outer membrane. The sac-1 locus could be linked to known antibiotic resistance markers on the gonococcal chromosome by genetic transformation.

摘要

一个影响对正常人血清杀菌活性易感性的基因座已被命名为sac-1。该基因座被证明与影响外膜蛋白1的第二个基因座(命名为nmp-2)紧密连锁,但并不相同。通过基因转化,sac-1基因座可与淋球菌染色体上已知的抗生素抗性标记相连。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/047e/351481/6281a81b9816/iai00163-0147-a.jpg

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