淋病奈瑟菌中血清抗性表型与精氨酸生物合成基因的共转化
Cotransformation of a serum resistance phenotype with genes for arginine biosynthesis in Neisseria gonorrhoeae.
作者信息
Spratt S K, Jones F, Shockley T E, Jackson J H
出版信息
Infect Immun. 1980 Jul;29(1):287-9. doi: 10.1128/iai.29.1.287-289.1980.
Abstract
Two genes (arg-3 and arp-6) marked by arginine auxotrophy and a gene (sac-2) marked by resistance to serum killing were found to be linked by cotransformation. Evidence derived from the linkage of these markers to spc (spectinomycin resistance) suggests that sac-2 may be genetically distinct from a sac gene previously described.
摘要
通过共转化发现了两个由精氨酸营养缺陷型标记的基因（arg-3和arp-6）以及一个由抗血清杀伤标记的基因（sac-2）。这些标记与spc（壮观霉素抗性）的连锁所获得的证据表明，sac-2在遗传上可能与先前描述的一个sac基因不同。
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本文引用的文献
1
NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION.淋病奈瑟菌。一、与克隆变异基因连锁的毒力。
J Bacteriol. 1963 Jun;85(6):1274-9. doi: 10.1128/jb.85.6.1274-1279.1963.
2
Low antibiotic resistance of gonococci causing disseminated infection.引起播散性感染的淋球菌抗生素耐药性低。
N Engl J Med. 1973 Jun 7;288(23):1221-2. doi: 10.1056/NEJM197306072882308.
3
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4
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7
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8
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9
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