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眼部网状细胞肉瘤。表现为视网膜脱离,玻璃体细胞上显示单克隆免疫球蛋白轻链。

Ocular reticulum cell sarcoma. Presentation as retinal detachment with demonstration of monoclonal immunoglobulin light chains on the vitreous cells.

作者信息

Michelson J B, Michelson P E, Bordin G M, Chisari F V

出版信息

Arch Ophthalmol. 1981 Aug;99(8):1409-11. doi: 10.1001/archopht.1981.03930020283017.

DOI:10.1001/archopht.1981.03930020283017
PMID:6789803
Abstract

A 61-year-old man with a history of cerebral reticulum cell sarcoma-microglioma (histiocytic lymphoma) in remission was initially seen with uveitis and exudative retinal detachment. Pars plana vitreous biopsy established the diagnosis by cytologic findings and allowed the immunofluorescent demonstration of a monoclonal immunoglobulin within the vitreous cells. Direct immunofluorescent microscopy of the vitreous infiltrate may prove to be of benefit in the workup of patients with uveitis in whom malignant lymphoma must be excluded.

摘要

一名61岁男性,曾患脑网状细胞肉瘤-小胶质细胞瘤(组织细胞性淋巴瘤),目前处于缓解期,最初表现为葡萄膜炎和渗出性视网膜脱离。经睫状体平坦部玻璃体活检,通过细胞学检查确诊,并通过免疫荧光法在玻璃体细胞中显示出单克隆免疫球蛋白。玻璃体浸润的直接免疫荧光显微镜检查可能有助于对必须排除恶性淋巴瘤的葡萄膜炎患者进行检查。

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1
Ocular reticulum cell sarcoma. Presentation as retinal detachment with demonstration of monoclonal immunoglobulin light chains on the vitreous cells.眼部网状细胞肉瘤。表现为视网膜脱离,玻璃体细胞上显示单克隆免疫球蛋白轻链。
Arch Ophthalmol. 1981 Aug;99(8):1409-11. doi: 10.1001/archopht.1981.03930020283017.
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Uveitis and reticulum cell sarcoma of brain with bilateral neoplastic seeding of vitreous without retinal or uveal involvement.葡萄膜炎与脑网状细胞肉瘤,伴有玻璃体双侧肿瘤播散,不累及视网膜或葡萄膜。
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Uveitis and cerebral reticulum-cell sarcoma (large-cell lymphoma). Case report.葡萄膜炎与脑网状细胞肉瘤(大细胞淋巴瘤)。病例报告。
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Trans Am Ophthalmol Soc. 2003;101:275-92.
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Diagnostic pars plana vitrectomy report of a 21-year retrospective study.一项21年回顾性研究的诊断性玻璃体切割术报告。
Trans Am Ophthalmol Soc. 1995;93:281-308; discussion 308-14.
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Intraocular T-cell lymphoma mimicking a ring melanoma. First manifestation of systemic disease. Report of a case and survey of the literature.酷似环状黑色素瘤的眼内T细胞淋巴瘤。系统性疾病的首发表现。病例报告及文献综述。
Graefes Arch Clin Exp Ophthalmol. 1994 Mar;232(3):148-52. doi: 10.1007/BF00176784.
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Br J Ophthalmol. 1988 Dec;72(12):905-11. doi: 10.1136/bjo.72.12.905.
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Intraocular non-Hodgkin's lymphoma treated with systemic and intrathecal chemotherapy and radiotherapy. A case report and review of the literature.采用全身及鞘内化疗和放疗治疗的眼内非霍奇金淋巴瘤。病例报告及文献复习
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