结核分枝杆菌菌株对利福平和异烟肼的耐药性。
Resistance to rifampicin and isoniazid in strains of Mycobacterium tuberculosis.
作者信息
Siddiqi S H, Aziz A, Reggiardo Z, Middlebrook G
出版信息
J Clin Pathol. 1981 Aug;34(8):927-9. doi: 10.1136/jcp.34.8.927.
Abstract
Drug susceptibility studies on strains of Mycobacterium tuberculosis isolated from widely different populations of patients and tested by two different techniques indicated that all 55 strains resistant to rifampicin were also resistant to isoniazid, while many strains resistant to isoniazid were found to be susceptible to rifampicin. This observation, which has as yet unknown laboratory and clinical significance, may be particularly useful in management of patients. Further studies are called for to establish this relation.
摘要
对从广泛不同患者群体中分离出的结核分枝杆菌菌株进行药敏研究，并采用两种不同技术进行检测，结果表明，所有55株对利福平耐药的菌株也对异烟肼耐药，而许多对异烟肼耐药的菌株对利福平敏感。这一观察结果的实验室和临床意义尚不清楚，可能对患者管理特别有用。需要进一步研究来确定这种关系。
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