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不同消毒剂用于表面气溶胶消毒的效用研究(作者译)

[Studies on the usefulness of different disinfectants for the aerosol disinfection of surfaces (author's transl)].

作者信息

Nicklas W, Böhm K H

出版信息

Zentralbl Bakteriol Mikrobiol Hyg B. 1981;173(5):365-73.

PMID:6792816
Abstract

In a glove-box made of stainless steel germ-carriers of lime-wood and aluminium were layed out after having been contaminated with different vegetative bacteria (Staphylococcus aureus, Streptococcus faecium, Pseudomonas aeruginosa, Proteus mirabilis). Disinfectant aerosols of several germicidal substances belonging to different chemical groups were brought into the glove-box. The aerosol was produced by a commercial generator. The following substances proved to have a good disinfectant effect under the conditions used: hydrogen peroxide, peracetic acid, formaldehyde, glutardialdehyde, beta-propiolacton, Lysoformin resp. Lysoformin 2000 and Tegodor 73, whereas triethylenglycol, phenol-derivatives (Gevisol, Environ), Chloramine 80 and detergents were not able to kill all the bacteria on the germ-carriers within 2 h. Determination of the natural mortality rate showed, that at relative humidities of over 58% the test bacteria die within 72 h on the germ-carriers without presence of disinfectants. At a relative humidity of 77%, Staphylococcus aureus on wooden germ-carriers died within 24 h.

摘要

在一个由不锈钢制成的手套箱中,将被不同的营养细菌(金黄色葡萄球菌、粪肠球菌、铜绿假单胞菌、奇异变形杆菌)污染后的椴木和铝制细菌载体摆放好。将属于不同化学组的几种杀菌物质的消毒气雾剂引入手套箱。气雾剂由商用发生器产生。结果证明,在所用条件下,以下物质具有良好的消毒效果:过氧化氢、过氧乙酸、甲醛、戊二醛、β-丙内酯、溶菌福明(Lysoformin)或溶菌福明2000(Lysoformin 2000)以及特戈多(Tegodor 73),而三甘醇、酚类衍生物(格维索尔(Gevisol)、安维隆(Environ))、氯胺80和洗涤剂在2小时内无法杀死细菌载体上的所有细菌。自然死亡率的测定表明,在相对湿度超过58%时,测试细菌在没有消毒剂的情况下,72小时内在细菌载体上死亡。在相对湿度为77%时,木制细菌载体上的金黄色葡萄球菌在24小时内死亡。

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