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外淋巴压力的实验研究

Experimental study on the perilymphatic pressure.

作者信息

Nagahara K, Fisch U, Dillier N

出版信息

Am J Otol. 1981 Jul;3(1):1-8.

PMID:6792925
Abstract

The hydrostatic pressure was successfully and accurately measured through the round window membrane of the cat over a wide pressure range and long duration using glass micropipets of 1-5 micrometer tip inner diameter and an active nulling pressure measuring system. The dynamic changes in perilymphatic pressure occurring after inhalation of different gas mixtures (5 percent CO2 and 95 percent O2/carbogen, 5 percent and 10 percent CO2 in room air) were recorded. The maximal oxygenation of the perilymph combined with minimal increase in pressure was achieved following inhalation of carbogen. The correlation between variations of pressure of the perilymph and of the systemic blood circulation shows that a regulatory system is present in the inner ear vessels. The pressure measuring system used has proven to have all the requirements that are needed for its use in humans.

摘要

使用内径为1 - 5微米的玻璃微吸管和有源归零压力测量系统,在很宽的压力范围和很长的时间内,成功且准确地测量了猫圆窗膜上的静水压力。记录了吸入不同气体混合物(5%二氧化碳和95%氧气/混合气、室内空气中5%和10%二氧化碳)后外淋巴压力的动态变化。吸入混合气后,外淋巴实现了最大程度的氧合,同时压力升高最小。外淋巴压力变化与体循环压力变化之间的相关性表明,内耳血管中存在一个调节系统。所使用的压力测量系统已证明具备用于人体所需的所有要求。

相似文献

1
Experimental study on the perilymphatic pressure.外淋巴压力的实验研究
Am J Otol. 1981 Jul;3(1):1-8.
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Effects of isosorbide on perilymphatic pressure and oxygenation.异山梨醇对外淋巴液压力和氧合作用的影响。
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Management of sudden deafness.突发性耳聋的治疗
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引用本文的文献

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Sensors (Basel). 2018 Oct 21;18(10):3565. doi: 10.3390/s18103565.
2
Cochlear blood flow related to hyperosmotic solution.
Arch Otorhinolaryngol. 1982;234(2):145-50. doi: 10.1007/BF00453621.
3
Maintenance of hydrostatic pressure gradients in the membranous labyrinth.膜迷路中流体静压梯度的维持。
Arch Otorhinolaryngol. 1989;246(1):65-6. doi: 10.1007/BF00454138.