Grand A, Huret J F, Farge C, Ferry M, Perret S P
Arch Mal Coeur Vaiss. 1981 Aug;74(8):909-16.
20 cases of pregnancy in women with complete atrioventricular block (AVB) (12 patients) or with permanent pacemakers (8 patients) were observed in a French cooperative series and compared with I30 previously reported cases. Most patients were asymptomatic but an increase in the number of syncopes during gestation might be observed : 4 out of 12 in our series. Although AVB remains functionally latent during pregnancy, regular cardio-obstetric follow-up is advised. Hospital admission a few days before the expected date of delivery is desirable, and it is essential that the patients are delivered in department specialised in high risk pregnancies. The need for prophylactic temporary pacing during delivery is not universally accepted. On the other hand, dizziness and syncope are clear cut indications for permanent cardiac pacing ; programmable pacers are excellent choices in young women of childbearing age ; nuclear pulse generators (Pu 238) do not seem to expose the mothers or foetus to serious complications. Rejection of pulse generators during pregnancy is rare. Nearly all mothers with AVB, whether paced or not, now have normal pregnancies resulting in normal viable children. This conduction defect is not therefore an indication for therapeutic abortion.
在一个法国合作研究系列中,观察了20例患有完全性房室传导阻滞(AVB)的孕妇(12例患者)或植入永久性起搏器的孕妇(8例患者),并与之前报道的130例病例进行了比较。大多数患者无症状,但妊娠期晕厥次数可能会增加:我们系列中的12例中有4例。虽然AVB在孕期功能上仍处于潜伏状态,但建议进行定期的心脏产科随访。在预计分娩日期前几天入院是可取的,并且患者必须在高危妊娠专科进行分娩。分娩期间预防性临时起搏的必要性尚未得到普遍认可。另一方面,头晕和晕厥是永久性心脏起搏的明确指征;可编程起搏器是育龄年轻女性的理想选择;核脉冲发生器(钚238)似乎不会使母亲或胎儿面临严重并发症。孕期脉冲发生器排斥反应很少见。几乎所有患有AVB的母亲,无论是否起搏,现在都有正常的妊娠,生出正常的存活婴儿。因此,这种传导缺陷不是治疗性流产的指征。