黑腹果蝇发育过程中乙醇脱氢酶水平的变化。
Changes in levels of alcohol dehydrogenase during the development of Drosophila melanogaster.
作者信息
Anderson S M, McDonald J F
出版信息
Can J Genet Cytol. 1981;23(2):305-13. doi: 10.1139/g81-032.
The results of an analysis of the biochemical basis of changes in alcohol dehydrogenase (E.C.1.1.1.1) activity over Drosophila development are presented. The data indicate that (1) the characteristic changes that occur in ADH activity over development are predominantly, it not exclusively, the result of quantitative changes in the amount of enzyme present rather than qualitative changes affecting the enzyme's specific activity and (2) the fluctuations in amount of ADH which occur during development are not the result of the only known form of post-translational modification capable of affecting the biochemical properties of the enzyme. We conclude that developmental changes in amount of ADH are most likely the result of fluctuations in the turnover of the ADH protein.
本文展示了对果蝇发育过程中乙醇脱氢酶（E.C.1.1.1.1）活性变化的生化基础进行分析的结果。数据表明：（1）发育过程中ADH活性发生的特征性变化主要（若非唯一）是由于酶量的定量变化而非影响酶比活性的定性变化所致；（2）发育过程中ADH量的波动并非能够影响该酶生化特性的唯一已知翻译后修饰形式的结果。我们得出结论，ADH量的发育变化很可能是ADH蛋白周转波动的结果。
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