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Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys.

作者信息

Lilja G, Graff-Lonnevig V, Bevegård S

出版信息

Allergy. 1983 Jan;38(1):31-5. doi: 10.1111/j.1398-9995.1983.tb00853.x.

DOI:10.1111/j.1398-9995.1983.tb00853.x
PMID:6404193
Abstract

Fourteen boys with a mean age of 12.2 years were studied with respect to the protective effect of ketotifen on exercise-induced asthma (EIA) in comparison with disodium cromoglycate (DSCG). All had a positive history of EIA and a post-exercise fall in FEV1 of more than 20%. A double blind cross-over technique was used with a 1 week wash-out period between the two treatment alternatives. Both drugs gave some, but not significant protection for EIA and no differences between the two active substances tested were found. Great individual differences in the response to the two drugs were noted.

摘要

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Comparison of the protective effect of ketotifen and disodium cromoglycate on exercise-induced asthma in asthmatic boys.
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引用本文的文献

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Does regular treatment with ketotifen inhibit bronchoconstriction induced by isocapnic hyperventilation?用酮替芬进行常规治疗是否能抑制等碳酸过度通气诱导的支气管收缩?
Br J Clin Pharmacol. 1987 Jul;24(1):100-2. doi: 10.1111/j.1365-2125.1987.tb03143.x.
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Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders.
酮替芬。对其药效学和药代动力学特性以及在哮喘和过敏性疾病中的治疗用途的综述。
Drugs. 1990 Sep;40(3):412-48. doi: 10.2165/00003495-199040030-00006.