超声检查对成人多囊肾疾病的症状前诊断
Presymptomatic diagnosis of adult onset polycystic kidney disease by ultrasonography.
作者信息
Wolf B, Rosenfield A T, Taylor K J, Rosenfield N, Gottlieb S, Hsia Y E
出版信息
Clin Genet. 1978 Jul;14(1):1-7. doi: 10.1111/j.1399-0004.1978.tb02053.x.
Results of an ongoing prospective study of progeny of patients with adult-onset polycystic kidney disease using grey-scale ultrasound and high-dose nephrotomography are reported. Six asymptomatic subjects out of 17 at risk for polycystic kidney disease were found by ultrasonography to have multiple renal cysts; this included two unrelated children aged 18 months and 6 y who had normal high-dose nephrotomography. We suggest that ultrasonography may be the method of choice for presymptomatic detection of polycystic kidney disease. Serial studies of at-risk individuals by sonography will be useful in determining the earliest age of detection, the latest age of ultrasonography presentation, and in following the natural history of polycystic kidney disease.
报告了一项正在进行的前瞻性研究结果，该研究使用灰阶超声和高剂量肾断层摄影术对成年多囊肾病患者的后代进行研究。在17名有患多囊肾病风险的无症状受试者中，超声检查发现6人有多个肾囊肿；其中包括两名无血缘关系的儿童，年龄分别为18个月和6岁，他们的高剂量肾断层摄影术结果正常。我们认为超声检查可能是多囊肾病症状前检测的首选方法。通过超声对有风险个体进行系列研究，将有助于确定最早检测年龄、超声检查出现的最晚年龄，并跟踪多囊肾病的自然病程。
Zotero 插件