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烧伤病房中铜绿假单胞菌的内源性和外源性感染

Endogenous and exogenous infection with Pseudomonas aeruginosa in a burns unit.

作者信息

Chitkara Y K, Feierabend T C

出版信息

Int Surg. 1981 Jul-Sep;66(3):237-40.

PMID:6797982
Abstract

Twenty patients who were admitted to the Burns Unit from December, 1969 through October, 1970 were studies to determine the sources of infection caused by Pseudomonas aeruginosa. The pyocine typing method was employed for finger printing of 383 isolates recovered from wounds and 67 isolates from environmental cultures of nurses' hands, sinks, floors, bed rails, walls and baths. In addition, cultures of moist rectal swabs were carried out daily for the first six days of hospitalization to assess the importance of endogenous infection. In six patients, the rectum was identified as the source of infection. However, in these patients, pyocine types of Ps. aeruginosa which were not obtained from rectal cultures, were also recovered. Pyocine types 1b, 10 and 31 were isolated more frequently than others. Clustering of common pyocine types suggests cross-contamination. Sinks were found to be consistently contaminated with Ps. aeruginosa. Amongst the environmental sources, positive cultures were occasionally obtained from floors, bed rails and nurses' hands. It is suggested that sinks are probably the most important reservoir of Pseudomonas infection in burns.

摘要

对1969年12月至1970年10月期间收治入烧伤科的20例患者进行了研究,以确定铜绿假单胞菌感染的来源。采用细菌素分型方法对从伤口分离出的383株菌株以及从护士手部、水槽、地板、床栏、墙壁和浴室的环境培养物中分离出的67株菌株进行指纹识别。此外,在住院的头六天每天进行直肠拭子培养,以评估内源性感染的重要性。在6例患者中,直肠被确定为感染源。然而,在这些患者中,也分离出了未从直肠培养物中获得的铜绿假单胞菌细菌素型。1b型、10型和31型细菌素比其他类型更频繁地被分离出来。常见细菌素型的聚类表明存在交叉污染。发现水槽一直被铜绿假单胞菌污染。在环境来源中,偶尔从地板、床栏和护士手部获得阳性培养物。提示水槽可能是烧伤患者中铜绿假单胞菌感染最重要的储存库。

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