• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

从淡水蓝藻霍氏伪枝藻中分离含氯抗生素。

Isolation of chlorine-containing antibiotic from the freshwater cyanobacterium Scytonema hofmanni.

作者信息

Mason C P, Edwards K R, Carlson R E, Pignatello J, Gleason F K, Wood J M

出版信息

Science. 1982 Jan 22;215(4531):400-2. doi: 10.1126/science.6800032.

DOI:10.1126/science.6800032
PMID:6800032
Abstract

Scytonema hofmanni, a filamentous freshwater cyanobacterium (blue-green alga), produces secondary metabolites which inhibit the growth of other cyanobacteria and green algae. A rapid, qualitative assay for this inhibition has been developed with Synechococcus as the test organism. This assay procedure has led to the isolation and characterization of an antibiotic (named cyanobacterin) from Scytonema. The antibiotic has a molecular weight of 430 and an empirical formula of C23H23O6Cl and contains a gamma-lactone and a chlorinated aromatic nucleus. It inhibits the growth of various algae but has limited effect on nonphotosynthetic bacteria or protozoans and thus may have potential use as a specific algicide.

摘要

霍氏伪枝藻是一种丝状淡水蓝细菌(蓝绿藻),能产生抑制其他蓝细菌和绿藻生长的次生代谢产物。已开发出一种以聚球藻为测试生物的快速定性抑制测定法。该测定程序已导致从霍氏伪枝藻中分离并鉴定出一种抗生素(命名为蓝藻素)。这种抗生素的分子量为430,经验式为C₂₃H₂₃O₆Cl,含有一个γ-内酯和一个氯化芳环。它能抑制多种藻类的生长,但对非光合细菌或原生动物的作用有限,因此可能有作为特定杀藻剂的潜在用途。

相似文献

1
Isolation of chlorine-containing antibiotic from the freshwater cyanobacterium Scytonema hofmanni.从淡水蓝藻霍氏伪枝藻中分离含氯抗生素。
Science. 1982 Jan 22;215(4531):400-2. doi: 10.1126/science.6800032.
2
Acute toxicity of the natural algicide, cyanobacterin, to Daphnia magna.天然除藻剂蓝藻素对大型溞的急性毒性
Ecotoxicol Environ Saf. 1990 Oct;20(2):167-74. doi: 10.1016/0147-6513(90)90055-a.
3
[Production of the antibiotic-algicide cyanobacterin LU-2 by a filamentous cyanobacterium Nostoc sp].[丝状蓝细菌念珠藻属产生抗生素-杀藻剂蓝细菌素LU-2]
Mikrobiologiia. 1991 Nov-Dec;60(6):21-5.
4
Activity of the natural algicide, cyanobacterin, on angiosperms.天然除藻剂——蓝藻素对被子植物的活性。
Plant Physiol. 1986 Apr;80(4):834-7. doi: 10.1104/pp.80.4.834.
5
Butenolide and furandione from an endophytic Aspergillus terreus.来自内生土曲霉的丁烯内酯和呋喃二酮。
Chem Pharm Bull (Tokyo). 2010 Sep;58(9):1221-3. doi: 10.1248/cpb.58.1221.
6
Isolation and structure determination of a proteasome inhibitory metabolite from a culture of Scytonema hofmanni.从霍氏伪枝藻培养物中分离和鉴定一种蛋白酶体抑制性代谢物的结构
J Microbiol Biotechnol. 2008 Oct;18(10):1655-8.
7
Broad spectrum and mode of action of an antibiotic produced by Scytonema sp. TISTR 8208 in a seaweed-type bioreactor.
Appl Biochem Biotechnol. 1998 Spring;70-72:249-56. doi: 10.1007/BF02920141.
8
Synthesis and algicidal activity of (+)-cyanobacterin and its stereoisomer.(+)-蓝藻素及其立体异构体的合成与杀藻活性
Biosci Biotechnol Biochem. 2005 Feb;69(2):391-6. doi: 10.1271/bbb.69.391.
9
New butenolides from two marine streptomycetes.来自两种海洋链霉菌的新型丁烯内酯
J Nat Prod. 2000 Nov;63(11):1570-2. doi: 10.1021/np0001676.
10
A novel hepatoprotective gamma-lactone, MH-031. I. Discovery, isolation, physico-chemical properties and structural elucidation.一种新型保肝γ-内酯,MH-031。I. 发现、分离、理化性质及结构解析。
J Antibiot (Tokyo). 1991 Aug;44(8):832-7. doi: 10.7164/antibiotics.44.832.

引用本文的文献

1
Regioselective Ru(ii)-catalyzed C-H alkenylation and annulation of indoles: a direct approach to fused lactone scaffolds.区域选择性钌(II)催化的吲哚C-H烯基化和环化反应:构建稠合内酯骨架的直接方法
RSC Adv. 2025 Aug 26;15(37):30135-30145. doi: 10.1039/d5ra03671b. eCollection 2025 Aug 22.
2
A Chemo-Enzymatic Platform for Furanolide Synthesis and Functional Exploration.用于呋喃内酯合成及功能探索的化学酶法平台
J Am Chem Soc. 2025 Aug 27;147(34):30979-30988. doi: 10.1021/jacs.5c08354. Epub 2025 Aug 15.
3
The Allelopathic Activity of Extracts and Isolated from .
从 中提取和分离得到的化感活性物质
Molecules. 2022 Jun 15;27(12):3852. doi: 10.3390/molecules27123852.
4
Biosynthesis of cyanobacterin, a paradigm for furanolide core structure assembly.蓝藻素的生物合成,呋喃内酯核心结构组装的典范。
Nat Chem Biol. 2022 Jun;18(6):652-658. doi: 10.1038/s41589-022-01013-7. Epub 2022 May 26.
5
Algae and Their Metabolites as Potential Bio-Pesticides.藻类及其代谢产物作为潜在的生物农药
Microorganisms. 2022 Jan 27;10(2):307. doi: 10.3390/microorganisms10020307.
6
Reviewing Interspecies Interactions as a Driving Force Affecting the Community Structure in Lakes via Cyanotoxins.将种间相互作用视为通过蓝藻毒素影响湖泊群落结构的驱动力进行综述。
Microorganisms. 2021 Jul 25;9(8):1583. doi: 10.3390/microorganisms9081583.
7
Heterologous production of cyanobacterial compounds.蓝细菌化合物的异源生产。
J Ind Microbiol Biotechnol. 2021 Jun 4;48(3-4). doi: 10.1093/jimb/kuab003.
8
Natural Products from Cyanobacteria: Focus on Beneficial Activities.蓝藻中的天然产物:关注有益活性。
Mar Drugs. 2019 May 30;17(6):320. doi: 10.3390/md17060320.
9
Distinctive characters of Nostoc genomes in cyanolichens.蓝藻地衣中念珠藻属基因组的独特特征。
BMC Genomics. 2018 Jun 5;19(1):434. doi: 10.1186/s12864-018-4743-5.
10
An Unusual Diterpene-Enhygromic Acid and Deoxyenhygrolides from a Marine Myxobacterium, Enhygromyxa sp.一种来自海洋粘细菌Enhyromyxa sp.的不寻常二萜类化合物——增强吸湿酸和脱氧增强吸湿内酯
Mar Drugs. 2017 Apr 6;15(4):109. doi: 10.3390/md15040109.