Gray Freshwater Biological Institute, University of Minnesota, Navarre, Minnesota 55392.
Plant Physiol. 1986 Apr;80(4):834-7. doi: 10.1104/pp.80.4.834.
Cyanobacterin is a secondary metabolite produced by the cyanobacterium (blue-green alga) Scytonema hofmanni. The compound had previously been isolated and chemically characterized. It was shown to inhibit the growth of algae at a concentration of approximately 5 micromolar. Cyanobacterin also inhibited the growth of angiosperms, including the aquatic, Lemna, and terrestrial species such as corn and peas. In isolated pea chloroplasts, cyanobacterin inhibited the Hill reaction when p-benzoquinone, K(3)Fe(CN)(6), dichlorophenolindophenol, or silicomolybdate were used as electron acceptors. The concentration needed to inhibit the Hill reaction in photosystem II was generally lower than the concentration of the known photosystem II inhibitor 3-(3,4-dichlorophenyl)-1,1-dimethyl urea. Cyanobacterin had no effect on electron transport in photosystem I. The data indicate that cyanobacterin inhibits O(2) evolving photosynthetic electron transport in all plants and that the most probable site of action is in photosystem II.
蓝藻菌抑素是由蓝藻（蓝绿藻）鱼腥藻产生的一种次生代谢产物。该化合物先前已被分离并进行了化学表征。它在大约 5 微摩尔的浓度下显示出抑制藻类生长的作用。蓝藻菌抑素还抑制了包括水生、浮萍和陆地物种（如玉米和豌豆）在内的被子植物的生长。在分离的豌豆叶绿体中，当使用对苯醌、K(3)Fe(CN)(6)、二氯苯酚靛酚或硅钼酸盐作为电子受体时，蓝藻菌抑素抑制了希尔反应。抑制光系统 II 希尔反应所需的浓度通常低于已知的光系统 II 抑制剂 3-(3,4-二氯苯基)-1,1-二甲基脲的浓度。蓝藻菌抑素对光系统 I 的电子传递没有影响。数据表明，蓝藻菌抑素抑制所有植物中释放氧气的光合作用电子传递，作用最可能的部位是在光系统 II。
