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68Ga-EDTA正电子发射断层扫描与透射计算机断层扫描在脑梗死评估中的比较

Positron emission tomography with 68Ga-EDTA compared with transmission computed tomography in the evaluation of brain infarcts.

作者信息

Ericson K, Bergström M, Eriksson L, Hatam A, Greitz T, Söderström C E, Widén L

出版信息

Acta Radiol Diagn (Stockh). 1981;22(4):385-98. doi: 10.1177/028418518102200401.

DOI:10.1177/028418518102200401
PMID:6800214
Abstract

The diagnostic value of positron emission tomography (PET) was evaluated in 41 examinations of 40 patients. 68Ga-EDTA was used as a positron source. The findings were correlated with those of conventional of CT scanning. A clearly pathologic accumulation of 68Ga-EDTA was detected in 29 of 41 PET scans. The precontrast CT scans were negative in 11 and non-conclusive in one patient. CT after administration of contrast medium was performed in 29 patients. Of these, 21 had a clearly pathologic PET scan and 14 had visible contrast enhancement on CT examination. The injury of the blood-brain barrier thus was better demonstrated with PET than with CT. The topologic diagnosis was, however, better demonstrated at CT. It seems that CT and PET are supplementary examinations and that PET is superior to CT in the detection of injury of or absence of the blood-brain barrier.

摘要

对40例患者的41次检查评估了正电子发射断层扫描(PET)的诊断价值。使用68Ga-EDTA作为正电子源。将结果与传统CT扫描结果进行关联。在41次PET扫描中,有29次检测到68Ga-EDTA明显的病理性聚集。11例患者的增强前CT扫描结果为阴性,1例患者的结果不明确。29例患者进行了造影剂增强CT检查。其中,21例PET扫描结果明显为病理性,14例在CT检查中有可见的造影剂增强。因此,PET比CT能更好地显示血脑屏障损伤。然而,CT在拓扑诊断方面表现更好。似乎CT和PET是互补检查,且PET在检测血脑屏障损伤或其缺失方面优于CT。

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引用本文的文献

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Quantitative assessment of blood-brain barrier permeability in multiple sclerosis using 68-Ga-EDTA and positron emission tomography.使用68镓-乙二胺四乙酸和正电子发射断层扫描对多发性硬化症血脑屏障通透性进行定量评估。
J Neurol Neurosurg Psychiatry. 1988 Aug;51(8):1058-62. doi: 10.1136/jnnp.51.8.1058.
3
The blood tumour barrier in intracranial tumours studied with X-ray computed tomography and positron emission tomography using 68-Ga-EDTA.使用68镓乙二胺四乙酸通过X射线计算机断层扫描和正电子发射断层扫描研究颅内肿瘤中的血肿瘤屏障。
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4
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