某些动物病毒的伽马射线灭活作用
Gamma ray inactivation of some animal viruses.
作者信息
Thomas F C, Davies A G, Dulac G C, Willis N G, Papp-Vid G, Girard A
出版信息
Can J Comp Med. 1981 Oct;45(4):397-9.
Abstract
Twenty samples of animal viruses comprising 14 different viruses in 12 families were subjected to varying doses of gamma irradiation from a 60Co source in a Gamma Cell 220 (Atomic Energy of Canada Limited) to determine lethal dose levels. The dose responses appeared linear throughout inactivation. The D10 values, that is the dose necessary to reduce infectivity by one log10, ranged from less than 0.20 Megarads to approximately 0.55 Megarads. There was not a complete inverse correlation between the target size (virion core) and the D10 value.
摘要
对来自12个科的14种不同病毒的20份动物病毒样本，在伽马细胞220（加拿大原子能有限公司）中用60Co源进行不同剂量的伽马辐射，以确定致死剂量水平。在整个灭活过程中，剂量反应呈线性。D10值，即使感染力降低一个对数级所需的剂量，范围从小于0.20兆拉德到约0.55兆拉德。目标大小（病毒粒子核心）与D10值之间不存在完全的负相关。
相似文献
1
Gamma ray inactivation of some animal viruses.某些动物病毒的伽马射线灭活作用
Can J Comp Med. 1981 Oct;45(4):397-9.
2
Inactivation of viral agents in bovine serum by gamma irradiation.
Can J Microbiol. 1990 Oct;36(10):737-40. doi: 10.1139/m90-126.
3
Inactivation by gamma irradiation of animal viruses in simulated laboratory effluent.γ射线辐照对模拟实验室废水中动物病毒的灭活作用
Appl Environ Microbiol. 1982 May;43(5):1051-6. doi: 10.1128/aem.43.5.1051-1056.1982.
4
5
Gamma irradiation of animal sera for inactivation of viruses and mollicutes--a review.用于病毒和支原体灭活的动物血清γ射线辐照——综述
Biologicals. 2011 Nov;39(6):370-7. doi: 10.1016/j.biologicals.2011.05.003. Epub 2011 Aug 25.
6
Inactivation of biohazards in healthcare wastewater by E-Beam and Gamma irradiation: a comparative study.电子束和伽马射线辐照对医疗废水生物危害的灭活作用：一项对比研究。
Environ Sci Pollut Res Int. 2022 Oct;29(50):75575-75586. doi: 10.1007/s11356-022-21159-0. Epub 2022 Jun 3.
7
Comparison of two different methods for inactivation of viruses in serum.血清中病毒灭活两种不同方法的比较。
Clin Diagn Lab Immunol. 1997 Sep;4(5):504-8. doi: 10.1128/cdli.4.5.504-508.1997.
8
[Sterilization by ionizing radiations (author's transl)].[电离辐射灭菌法（作者译）]
Rev Epidemiol Sante Publique. 1976 Mar-Apr;24(2):165-84.
9
Inactivation of viral and prion pathogens by gamma-irradiation under conditions that maintain the integrity of human albumin.在保持人白蛋白完整性的条件下，通过γ射线辐照使病毒和朊病毒病原体失活。
Vox Sang. 2003 Jan;84(1):36-44. doi: 10.1046/j.1423-0410.2003.00256.x.
10
Inactivation and stability of viral diagnostic reagents treated by gamma radiation.经伽马辐射处理的病毒诊断试剂的灭活与稳定性
Biologicals. 1990 Oct;18(4):271-80. doi: 10.1016/1045-1056(90)90029-y.
引用本文的文献
1
Treatment of waxborne honey bee (Hymenoptera: Apidae) viruses using time, temperature, and electron-beam irradiation.利用时间、温度和电子束辐照处理蜡质蜜蜂（膜翅目：蜂科）病毒。
J Econ Entomol. 2024 Feb 12;117(1):34-42. doi: 10.1093/jee/toad216.
2
The inactivation and destruction of viruses by reactive oxygen species generated through physical and cold atmospheric plasma techniques: Current status and perspectives.通过物理和冷等离体技术产生的活性氧对病毒的灭活和破坏：现状与展望。
J Adv Res. 2023 Jan;43:59-71. doi: 10.1016/j.jare.2022.03.002. Epub 2022 Mar 9.
3
Viral inactivation by light.光致病毒失活
eLight. 2022;2(1):18. doi: 10.1186/s43593-022-00029-9. Epub 2022 Sep 26.
4
In Vitro Inactivation of SARS-CoV-2 Using Gamma Radiation.利用伽马辐射对严重急性呼吸综合征冠状病毒2进行体外灭活
Appl Biosaf. 2020 Sep 1;25(3):157-160. doi: 10.1177/1535676020934242.
5
Pre-clinic study of radiopharmaceutical for Covid-19 inactivation: Dose distribution with Monte Carlo Simulation.用于新冠病毒灭活的放射性药物的临床前研究：蒙特卡罗模拟的剂量分布。
Appl Radiat Isot. 2022 Oct;188:110364. doi: 10.1016/j.apradiso.2022.110364. Epub 2022 Jul 8.
6
Radiation Inactivation of Coronavirus Infection Pathogen by the Example of Transmissible Gastroenteritis Virus.以传染性胃肠炎病毒为例探讨冠状病毒感染病原体的辐射灭活作用
Biophysics (Oxf). 2021;66(4):589-595. doi: 10.1134/S000635092104014X. Epub 2021 Oct 15.
7
Effect of gamma irradiation on filtering facepiece respirators and SARS-CoV-2 detection.伽马射线辐照对过滤式面罩呼吸器和 SARS-CoV-2 检测的影响。
Sci Rep. 2021 Oct 6;11(1):19888. doi: 10.1038/s41598-021-99414-6.
8
Gamma irradiation-mediated inactivation of enveloped viruses with conservation of genome integrity: Potential application for SARS-CoV-2 inactivated vaccine development.γ射线辐照介导的包膜病毒灭活与基因组完整性的保留：在严重急性呼吸综合征冠状病毒2（SARS-CoV-2）灭活疫苗开发中的潜在应用
Open Life Sci. 2021 Jun 2;16(1):558-570. doi: 10.1515/biol-2021-0051. eCollection 2021.
9
X-ray inactivation of RNA viruses without loss of biological characteristics.X 射线使 RNA 病毒失活而不丧失生物学特性。
Sci Rep. 2020 Dec 8;10(1):21431. doi: 10.1038/s41598-020-77972-5.
10
Sterility of gamma-irradiated pathogens: a new mathematical formula to calculate sterilizing doses.辐照病原体的无菌性：一种计算灭菌剂量的新数学公式。
J Radiat Res. 2020 Nov 16;61(6):886-894. doi: 10.1093/jrr/rraa076.
本文引用的文献
1
Preparation of non-infective soluble antigens with gamma radiation.用伽马辐射制备非感染性可溶性抗原。
Can J Microbiol. 1961 Apr;7:135-9. doi: 10.1139/m61-018.
2
Inactivation of thirty viruses by gamma radiation.通过伽马辐射使三十种病毒失活。
Appl Microbiol. 1971 Jul;22(1):61-5. doi: 10.1128/am.22.1.61-65.1971.
3
Recovery of viruses from field samples of raw, digested, and lagoon-dried sludges.从生污泥、消化污泥和泻湖干燥污泥的现场样本中回收病毒。
Bull World Health Organ. 1979;57(1):105-8.
4
Polioviruses and other enteroviruses in urban sewage from Laval (Canada): presence of non-vaccinal strains of poliovirus.加拿大拉瓦尔城市污水中的脊髓灰质炎病毒及其他肠道病毒：脊髓灰质炎病毒非疫苗株的存在情况
Can J Microbiol. 1979 Nov;25(11):1305-9. doi: 10.1139/m79-206.
Zotero 插件