被动转移迟发型超敏反应表达的非H-2限制
Non-H-2 restriction of expression of passively transferred delayed sensitivity.
作者信息
Berche P A, North R J
出版信息
J Exp Med. 1982 May 1;155(5):1334-43. doi: 10.1084/jem.155.5.1334.
Abstract
The results of this study of allogeneic restriction of passively transferred delayed sensitivity to Listeria antigens serve to illustrate the complexity of in vivo models. They show that the H-2 restriction observed when delayed-type hypersensitivity was transferred between H-2-congenic strains was no more severe than the restriction observed when delayed-type hypersensitivity was transferred between parental and F1 mice and between different strains sharing the same H-2 haplotype. It is obvious that genes, in addition to those of the H-2 locus, can be responsible for allogeneic restriction in vivo.
摘要
这项关于对李斯特菌抗原被动转移迟发型超敏反应的同种异体限制的研究结果，有助于阐明体内模型的复杂性。结果表明，当迟发型超敏反应在H-2同源品系之间转移时观察到的H-2限制，并不比在亲代与F1代小鼠之间以及具有相同H-2单倍型的不同品系之间转移迟发型超敏反应时观察到的限制更严重。显然，除了H-2基因座的基因外，其他基因也可能在体内导致同种异体限制。
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