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产酸型酸奶对黄曲霉毒素B1的解毒作用

Detoxification of aflatoxin B1 by acidogenous yoghurt.

作者信息

Megalla S E, Hafez A H

出版信息

Mycopathologia. 1982 Feb 19;77(2):89-91. doi: 10.1007/BF00437389.

Abstract

Serial concentrations of aflatoxin B1 ranged from 200 to 1000 p.p.b. were assayed for detoxification by acidogenous yoghurt. Thin-layered chromatography analysis revealed a complete transformation of 800 p.p.b. of aflatoxin B1 to a new fluorescing compound corresponding to aflatoxin B2a which is referred as hydroxydihydroaflatoxin B1. Partial conversion was present in yoghurt sample containing 1000 p.p.b. Toxicity test on chicken, confirmed Ciegler findings.

摘要

对浓度范围为200至1000 ppb的黄曲霉毒素B1系列浓度进行了产酸酸奶解毒测定。薄层色谱分析显示,800 ppb的黄曲霉毒素B1完全转化为一种与黄曲霉毒素B2a相对应的新的荧光化合物,即羟基二氢黄曲霉毒素B1。含有1000 ppb的酸奶样品中存在部分转化。对鸡的毒性试验证实了西格勒的研究结果。

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