Mogi G, Lim D J, Watanabe N
Arch Otolaryngol. 1982 May;108(5):270-5. doi: 10.1001/archotol.1982.00790530006003.
The immunoglobulin composition of perilymph (PL) was measured using electroimmunodiffusion, and transfer of serum antibodies to PL was studied using a passive hemagglutination test in chinchillas and guinea pigs. The mean values of IgG an albumin in PL were two to four times greater than those in CSF. In guinea pigs, IgA was found in 93% of the PL and 32% of the CSF samples, but in chinchillas only trace amounts of IgA were found in 50% of the PL and 15% of the CSF samples. No IgM was detected in PL or CSF of either species. This study suggests that a greater portion of the immunoglobulins in PL probably is derived from perilymphatic blood vessels as a filtrate and that the perilymphatic inner ear immune system is independent from that of the CSF.
采用电免疫扩散法测定外淋巴（PL）的免疫球蛋白组成，并利用被动血凝试验在栗鼠和豚鼠中研究血清抗体向PL的转移情况。PL中IgG和白蛋白的平均值比脑脊液（CSF）中的高两到四倍。在豚鼠中，93%的PL样本和32%的CSF样本中发现了IgA，但在栗鼠中，仅50%的PL样本和15%的CSF样本中发现了微量IgA。两种动物的PL或CSF中均未检测到IgM。本研究表明，PL中较大比例的免疫球蛋白可能作为滤过液来源于外淋巴管，并且内耳外淋巴免疫系统独立于CSF的免疫系统。
