在牛胎儿肾细胞上获得的人用狂犬病疫苗的区带离心纯化。生物学结果。
Zonal centrifuge purification of human rabies vaccine obtained on bovine fetal kidney cells. Biological results.
作者信息
Atanasiu P, Tsiang H, Reculard P, Aguilon F, Lavergne M, Adamovicz P
出版信息
Dev Biol Stand. 1978;40:35-44.
PMID:680400
Abstract
An inactivated human rabies vaccine prepared on bovine fetal kidney cells is concentrated and purified by zonal centrifugation. The peak of rabies particles is monitored by hemagglutination. Immunogenicity of the purified particles was evaluated by titration of specific antibodies from vaccinated animals. Protective activity of the vaccine was assayed on guinea pigs challenged with street rabies. Biological results were compared with those obtained with other tissue culture vaccines.
摘要
一种在牛胎儿肾细胞上制备的人用狂犬病灭活疫苗通过区带离心进行浓缩和纯化。通过血凝反应监测狂犬病颗粒的峰值。通过滴定接种动物的特异性抗体来评估纯化颗粒的免疫原性。在接种街毒株狂犬病病毒的豚鼠身上测定该疫苗的保护活性。将生物学结果与其他组织培养疫苗所获得的结果进行比较。
相似文献
1
2
[Zonal centrifuge purification of human rabies vaccine obtained on bovine foetal kidney cells (author's transl)].[从牛胎儿肾细胞获得的人用狂犬病疫苗的区带离心纯化法（作者译）]
Ann Microbiol (Paris). 1977 Aug-Sep;128(2):297-302.
3
Purification, potency and immunogenicity analysis of Vero cell culture-derived rabies vaccine: a comparative study of single-step column chromatography and zonal centrifuge purification.Vero细胞培养狂犬病疫苗的纯化、效价及免疫原性分析：单步柱色谱法与区带离心法纯化的比较研究
Microbes Infect. 2005 Jul;7(9-10):1110-6. doi: 10.1016/j.micinf.2005.03.034.
4
Purified chick embryo cell (PCEC) rabies vaccine for human use. Laboratory data.人用精制鸡胚细胞狂犬病疫苗。实验室数据。
Behring Inst Mitt. 1984 Nov(76):142-54.
5
6
Production of an inactivated rabies vaccine in primary dog kidney cells.
Dev Biol Stand. 1978;40:69-75.
7
Zonal-centrifuged human diploid cell rabies vaccine.区带离心人二倍体细胞狂犬病疫苗
Dev Biol Stand. 1976;37:267-71.
8
Zonal-centrifuged purified duck embryo cell culture rabies vaccine for human vaccination.用于人类接种的区带离心纯化鸭胚细胞培养狂犬病疫苗。
Appl Microbiol. 1971 Sep;22(3):358-65. doi: 10.1128/am.22.3.358-365.1971.
9
10
Live vaccinia-rabies virus recombinants, but not an inactivated rabies virus cell culture vaccine, protect B-lymphocyte-deficient A/WySnJ mice against rabies: considerations of recombinant defective poxviruses for rabies immunization of immunocompromised individuals.活痘苗 - 狂犬病病毒重组体，而非灭活的狂犬病病毒细胞培养疫苗，可保护B淋巴细胞缺陷的A/WySnJ小鼠免受狂犬病侵害：关于用于免疫功能低下个体狂犬病免疫的重组缺陷痘病毒的思考。
Vaccine. 2004 Sep 3;22(25-26):3329-33. doi: 10.1016/j.vaccine.2004.02.039.
引用本文的文献
1
Kinetics of different specific immunological parameters after rabies vaccination in mice.小鼠接种狂犬病疫苗后不同特异性免疫参数的动力学
Infect Immun. 1979 Jun;24(3):600-5. doi: 10.1128/iai.24.3.600-605.1979.
Zotero 插件