单克隆丙种球蛋白病中的独特型外周血淋巴细胞
Idiotypic peripheral blood lymphocytes in monoclonal gammopathy.
作者信息
Bast E J, van Camp B, Reynaert P, Wiringa G, Ballieux R E
出版信息
Clin Exp Immunol. 1982 Mar;47(3):677-82.
Abstract
Using two sets of anti-idiotypic antibody reagents (from guinea-pig and rabbit origin), idiotypic peripheral blood lymphocytes (PBL) could be shown in multiple myeloma (MM) patients in relapse, but not in remission. In patients having the benign form of monoclonal gammopathy (BMG), idiotypic lymphocytes were lacking except in some patients which were depicted as a `high risk' group, by a multivariate rating system. If present, idiotypic lymphocytes accounted for 1-4% of PBL.
摘要
使用两组抗独特型抗体试剂（源自豚鼠和兔子），在复发的多发性骨髓瘤（MM）患者中可检测到独特型外周血淋巴细胞（PBL），而缓解期患者则未检测到。在患有良性单克隆丙种球蛋白病（BMG）的患者中，除了一些被多变量评分系统描述为“高危”组的患者外，均未检测到独特型淋巴细胞。如果存在独特型淋巴细胞，其占外周血淋巴细胞的1 - 4%。
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本文引用的文献
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