Suzuki J, Yoshimoto T, Kodama N, Sakurai Y, Ogawa A
Surg Neurol. 1982 May;17(5):325-32. doi: 10.1016/0090-3019(82)90301-9.
Ten patients were treated with systemic administration of mannitol followed by blood substitute (perfluorochemicals) in the acute period of cerebral infarction in order to suppress the development of infarction and progressive deterioration. This chemotherapy was followed by reconstructive vascular surgery. There were 8 patients with cerebral infarction and 2 others in whom cerebral vascular occlusion occurred during an operation. Due to this treatment, there was no case in which the patient's condition was aggravated or in which death occurred. At examination two months later, 8 of the 10 patients had returned to productive lives. We consequently believe that this therapeutic method may prove to be an effective means of treating cerebral infarction in the acute stage. It is also thought that this method is applicable in surgical cases in which long-term vascular occlusion is required.
10例脑梗死急性期患者接受了全身给予甘露醇随后输注血液代用品（全氟化合物）的治疗，以抑制梗死灶的发展和病情的进行性恶化。该化疗之后进行了血管重建手术。其中8例为脑梗死患者，另外2例在手术过程中发生脑血管闭塞。由于采用了这种治疗方法，没有出现患者病情加重或死亡的情况。在两个月后的检查中，10例患者中有8例已恢复正常生活。因此，我们认为这种治疗方法可能是治疗急性期脑梗死的一种有效手段。还认为这种方法适用于需要长期血管闭塞的手术病例。
