Suzuki J, Yoshimoto T, Kodama N, Sakurai Y, Ogawa A
No Shinkei Geka. 1982 Dec;10(12):1273-80.
Ten cases were treated with systematic administration of mannitol followed by the blood substitute, perfluorochemicals, in the acute period of cerebral infarction in order to suppress the development of infarction and progressive deterioration. This chemotherapy was followed by reconstructive vascular surgery. There were 8 cases of cerebral infarction and 2 other cases in which cerebral vascular occlusion occurred during surgery. Due to this treatment, there were no cases of aggravated condition or death and at the time of follow-up examination after 2 months, and 8 of the ten patients returned to productive lives. We consequently believe that this therapeutic method may prove to be the effective means for treating cerebral infarction in the acute period. It is also thought that this method is applicable in surgical cases where long-term vascular occlusion is required.
在脑梗死急性期，对10例患者进行了系统的甘露醇给药治疗，随后给予血液代用品全氟化合物，以抑制梗死的发展和病情的进行性恶化。这种化疗之后进行了血管重建手术。其中有8例脑梗死患者，另外2例在手术过程中发生脑血管闭塞。由于采用了这种治疗方法，没有出现病情加重或死亡的病例，在2个月后的随访检查时，10名患者中有8名恢复了正常生活。因此，我们认为这种治疗方法可能是治疗急性期脑梗死的有效手段。还认为这种方法适用于需要长期血管闭塞的手术病例。
