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短期细菌生物测定中氯酚暴露顺序的影响。

Effect of sequence of exposure to chlorophenols in short-term bacterial bioassays.

作者信息

Trevors J T, Mayfield C I, Inniss W E

出版信息

Arch Environ Contam Toxicol. 1982;11(2):203-7. doi: 10.1007/BF01054897.

DOI:10.1007/BF01054897
PMID:6807218
Abstract

A bioassay using Pseudomonas fluorescens was affected by the sequence of exposure to pentachlorophenol (PCP) and 2,3,4,5-tetrachlorophenol (TCP). Surviving cells from standardized cell suspensions initially treated with PCP at concentrations ranging from 10 to 75 micrograms/ml, followed by removal of the toxicant, were not affected by a second dose of PCP at the same concentration. However, if the second dose was TCP, the test organism was sensitive to the second exposure. The most toxic sequence was an initial exposure to TCP followed by a second exposure to PCP. The response of the test organism to PCP and TCP was clearly dependent upon both the toxicant concentrations used and the sequence of toxicant addition.

摘要

使用荧光假单胞菌进行的生物测定受到接触五氯苯酚(PCP)和2,3,4,5-四氯苯酚(TCP)顺序的影响。最初用浓度范围为10至75微克/毫升的PCP处理标准化细胞悬液,然后去除毒物,存活细胞不受相同浓度的第二剂PCP影响。然而,如果第二剂是TCP,受试生物对第二次接触敏感。毒性最大的顺序是最初接触TCP,然后第二次接触PCP。受试生物对PCP和TCP的反应显然取决于所用毒物浓度和毒物添加顺序。

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